Measurement TechniquesNon-invasive quantification of diaphragm kinetics using m-mode sonography Purpose: The standard conditions of spirometry (i.e., wearing a noseclip and breathing through a mouthpiece and a pneumotachograph) are likely to alter the ventilatory pattern. We used "time-motion" mode (M-mode) sonography to assess the changes in diaphragm kinetics induced by spirometry during quiet breathing.Methods: An M-mode sonographic study of the right diaphragm was performed before and during standard spirometry in eight pa~ents without respiratory disease (age 34 to 68 yr).Results: During spirometry, the diaphragm inspiratory amplitude (DIA) increased from 1.34 + 0.18 cm to 1.80 + 0, 18 cm (P = 0,007), whereas the diaphragmatic inspiratory time (T, diaph) increased from 1.27 -+_ 0.15 to 1.53 + 0.23 sec, (P = 0.015), without change in diaphragmatic total time interval (-I-tot diaph). Therefore, the diaphragm duty cycle (T, diaph /Ttot diaph) increased from 38% +--I% to 44% _ 496 (P = 0.023). The diaphragm inspiratory (DIV) and expiratory (DEV) motion velocity increased (P = 0.007).Conclusion: M-mode sonography enabled us to demonstrate that the wearing of a nose clip and breathing through a mouthpiece and a pneumotachograph induce measurable changes in diaphragm kinetics.Object-if : Les conditions de la spirom&ne standard (c.-,~-d. le port du pince-nez et la respiration ~ travers un embout buccal et un pneumotacographe) sont susceptibles d'altErer la morphologie de la ventilation. Nous avons utilisE le mode ~temps-amplitude,, (mode M) de la sonographie pour 6valuer les changements de la cinEtique diaphragmatique provoquEs par la spiromEtne pendant la respiration de repos.R~sultats : Pendant la spiromEtrie, I'amplitude inspiratoire diaphragmataque augmentait de 1,34 + 0, 18 ~ 1,80 +-0, 18 cm (P = 0,007), alors que le temps diaphragmatique inspiratoire (T, diaph) augmentmt de 1,27 _+ 0, I 5 ,~ 1,53 z 0,23 sec (P = 0,015), sans changement du temps diaphragmatique total (Trot diaph). Par consequent, le temps de I'activitE diaphragmatique (T, diaph/Ttot diaph) augmentait de 38 +_ I 96 ,~ 44 + 496 (P=0,023). La v41ocit4 de I'amplitude inspiratolre et expiratoire augmentait (P = 0,007).Conclusion : La sonographie en mode M nous a permis de dEmontrer que le port du pince-nez et la respiration h travers un embout buccal et un pneumotacographe provoquent des changements tangibles de la cin4tique diaphragmatique.From the