Tactile maps are essential tools for visually impaired people to comprehend space and to support the simple pedestrian trips made difficult by their disability. Tactile maps are created manually and printed by specialists, and it takes a large amount of time to create a new one, which prevents using them on demand for everyday use. As a consequence, researchers and cartographers try to automate this creation process, but the existing automated derivation processes do not include generalization or advanced stylization steps, which limits their effectiveness. This paper reports first experiments to include such complex automated cartography processes to provide on demand tactile maps for visually impaired people. These first experiments were more intended to raise real research issues than solve them, and the paper discusses these issues in a research agenda to achieve automatically derived tactile maps.
's diseaseMagnetic resonance (MR) provides a non--invasive way to investigate changes in the brain resulting from aging or neurodegenerative disorders such as Alzheimer's disease (AD). Performing accurate analysis for population studies is challenging because of the interindividual anatomical variability. A large set of tools are found to perform studies of brain anatomy and population analysis (FreeSurfer, SPM, FSL). In this paper we present a newly developed surface--based processing pipeline (milxCTE) that allows accurate vertex--wise statistical comparisons of brain modifications, such as cortical thickness (CTE). The brain is first segmented into the three main tissues: white matter, gray matter and cerebrospinal fluid, after CTE is computed, a topology corrected mesh is generated. Partial inflation and non--rigid registration of cortical surfaces to a common space using shape context are then performed. Each of the steps was firstly validated using MR images from the OASIS database. We then applied the pipeline to a sample of individuals randomly selected from the AIBL study on AD and compared with FreeSurfer. For a population of 50 individuals we found correlation of cortical thickness in all the regions of the brain (average r =0.62 left and r =0.64 right hemispheres). We finally computed changes in atrophy in 32 AD patients and 81 healthy elderly individuals. Significant 2 differences were found in regions known to be affected in AD. We demonstrated the validity of the method for use in clinical studies which provides an alternative to well established techniques to compare different imaging biomarkers for the study of neurodegenerative diseases.
Mesh segmentation and semantic annotation are used as preprocessing steps for many applications, including shape retrieval, mesh abstraction, and adaptive simplification. In current practice, these two steps are done sequentially: a purely geometrical analysis is employed to extract the relevant parts, and then these parts are annotated. We introduce an original framework where annotation and segmentation are performed simultaneously, so that each of the two steps can take advantage of the other. Inspired by existing methods used in image processing, we employ an expert's knowledge of the context to drive the process while minimizing the use of geometric analysis. For each specific context a multi-layer ontology can be designed on top of a basic knowledge layer which conceptualizes 3D object features from the point of view of their geometry, topology, and possible attributes. Each feature is associated with an elementary algorithm for its detection. An expert can define the upper layers of the ontology to conceptualize a specific domain without the need to reconsider the elementary algorithms. This approach has a twofold advantage: on one hand it allows to leverage domain knowledge from experts even if they have limited or no skills in geometry processing and computer program-
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