Hemoglobin G Taegu, an electrophoretically slow hemoglobin with a structural anomaly believed to be in the beta-T-3 section of the beta chain, was the only variant found among 6700 normal Koreans. Four subjects, 0.06 percent, had the G-hemoglobin variant in addition to normal hemoglobin A. Hemoglobin E, known in numerous groups from Southeast Asia and the variant most frequently seen in Chinese subjects, was not found among the Koreans we tested.

Hemoglobin G Taegu, an electrophoretically slow hemoglobin variant found in four among 6700 apparently normal Korean subjects, has been shown to have a structural anomaly at position 22 of the beta‐chain where an alanyl residue occurs in place of the glutamyl group normally found at that position in Hemoglobin A.The same structural anomaly initially was established by other workers in slow hemoglobin variants occurring in North American Indians and more recently has been reported in a Northern Chinese subject. The identical hemoglobins in the three ethnic groups are Hemoglobins G Coushatta, found in several Alabama‐Coushatta Indians in Tex.; G Saskatoon, seen in a few descendants of Santee Indians currently living in Canada; G Hsin‐Chu, in a Chinese from the northern province of Liaoning and currently living in Taiwan; and G Taegu in Koreans.It is assumed that the Chinese and Korean subjects have the same hemoglobin variant because of gene flow. No similar assumption connecting these two groups with the North American Indian subjects is considered warranted with the presently limited available information.

No abstract

No abstract

No abstract