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In a recent paper [2] about the immune adherence phenomenon, which consists in agglutination of human erythrocytes when exposed to an antigen sensitized with antibody and complement [3,5], we have reported that not all the human blood samples are suitable for the reaction: there are erythrocytes of some individuals which do not agglutinate over a wide range of concentration of antibody and complement, while others show various patterns of reactivity. Repeated examinations with erythrocytes from the same individuals (obtained a t different times) showed the type of reactivity of erythrocytes to be a fixed property of the individual.The different patterns of reactivity of erythrocytes from different donors could be related to the presence or absence of surface receptors of the red cells which are commonly supposed to be instrumental in enabling the erythrocytes of primates t o function in the immuneadherence phenomenon.The present work has been carried out in order to investigate whether these differences in reactivity could be a reflection of a genetic polymorphism of erythrocytes. Materials and MethodsThe material for genetic investigation consisted of randomly selected Jewish families, mostly of Moroccan and Iranian origin. A sample consisting of parents from these families who were not blood relatives, 13 Vox Sang., Val. 10, No. 2 (1965)

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