Background: Candidal infections have increased significantly in denture wearers, especially in immunocompromised patients. The increase in resistance to existing antifungal drugs and number of patients at risk, in conjunction with the restricted number of commercially available antifungal drugs that still present many side effects, are the cause for this problem. These limitations emphasize the need to develop new and more effective antifungal agents with lesser side effects. Materials and Methods: The present study was undertaken to investigate the possible antifungal action of the alcoholic extract of different concentrations of Curcuma longa on four dilutions of Candida albicans (1:10, 1:20, 1:40 and 1:80) and to determine its minimum inhibitory concentration (MIC) and minimum fungicidal concentration using Sabouraud's agar medium. Results: There was complete inhibition of the growth of all four dilutions of Candida at a concentration of 800 μl which is considered as the MIC of alcoholic extract of turmeric on C. albicans , and the minimum fungicidal concentration was at 1600 μl. Conclusion: This study indicates a potent antifungal action of C. longa against C. albicans .
Abstract:Background: Xerostomia is a common clinical problem, and diff erent medications have been tried in its management. In the present study, routine dietary products are used to assess their eff ect on salivary fl ow. Aim: To assess the effi cacy of yogurt and lemon juice on increase in salivation and its comparison with that of unstimulated saliva. Materials and Methods: A total of 40 volunteers (aged 19-48) were selected. The pH of yogurt was calculated, and equivalent pH lemon juice was prepared. First, normal resting saliva was collected as baseline followed by every 1 min for 5 min. Patients were given lemon juice or yogurt and then crossed over to the other group to assess the impact of the stimulants on salivary fl ow from 1 to 5 min. Results: The results were analyzed statistically. Comparisons between baseline saliva secretion and that by yogurt and lemon juice (using the ANOVA test) showed that there was a signifi cant increase after treatment at the end of the experiment for both yogurt and lemon juice. However, yogurt showed a signifi cant increase in saliva secretion compared to baseline than lemon juice. Conclusions: Our fi ndings suggest that yogurt is a potential candidate for the treatment of dry mouth.
Introduction: Tumours arising from odontogenic tissues are rare and constitute a heterogeneous group of interesting lesions. Studies on incidence of Odontogenic Tumours (OT) published from many countries show a distinct geographic variation. Aim: The aim of present study was to compare and correlate the frequency of individual OT in India as well as the other parts of the world based on 2005 World Health Organization (WHO) classification. Materials and Methods: This institution-based retrospective study conducted in Department of Oral Pathology and Microbiology at Government Dental College and Research Institute, Bengaluru, Karnataka, India, from April 2015 to September 2016. Total of 122 cases of odontogenic tumours documented in duration of 10 years (2005 to 2014) were categorised based on World Health Organization 2005 classification. The histological type, age, gender, anatomical site and symptoms were systematically tabulated. Results: Odontogenic tumours constituted 9.5% (122 cases) of the total oral biopsies (1284 cases) received in a 10 year period. Among these, 95.9% of the tumours were benign and 4.1% were malignant. The most frequent tumour being ameloblastomas 39.3% followed by keratocystic odontogenic tumour 35.2%, odontome 4.9%, calcifying cystic odontogenic tumour 4.9% and adenomatoid odontogenic tumour 4%. While odontome, generally regarded as the most frequent OT in American and European countries, only accounted for 4.9%, the third most common tumour in the present study. The mean age of patients was 32.37 years (range: 9-70 years). Their exist a slight male predominance, more predilection to posterior region of mandible and majority of tumours presented with pain and swelling. Conclusion: The relative frequency of Odontogenic tumours reported in our institution was similar to the studies reported in India, Asian and African population but differs from that of European and American countries. There is a definite geographic variation in the prevalence of OT published worldwide.
Introduction Fungal infections have increased significantly contributing to the cause of morbidity and mortality. The increase in antimicrobial resistance and number of patients at risk in conjunction with the restricted number of commercially available antifungal drugs that still present many side effects are the cause for this problem. These limitations emphasize the need to develop new and more effective antifungal agents.Materials and Methods The present study was undertaken to investigate the possible antifungal action of the alcoholic extract of Curcuma longa in different concentrations on four dilutions of candida albicans 110 120 140 180 and to determine its Minimum Inhibitory Concentration MIC using Seaboardrsquos agar medium.Results There was complete inhibition of the growth of all four dilutions of Candida at a concentration of 800 microl which is considered as the Minimum Inhibitory Concentration MIC of alcoholic extract of turmeric on Candida albicans.Conclusion The study indicates a potent antifungal action of C. longa against Candida albicans.
Among the many aspects important in a child's development is sleep. Sleep disorderscan impair children's sleep and result in negative consequences. Obstructive sleep apnea (OSA)is one such disorder which involves blockage of the airway during sleep. The impact of OSA on the growth and development of a child may have detrimental effects on health, neuropsychological development and quality of life.One of the main causes of childhood OSA is hypertrophic adenoids and tonsils. As dentists often look into children's mouth, they can play an active role in identifying those with enlarged tonsils and referring them for sleep assessment.Therapeutic measures include not only surgical extraction of hypertrophic adenoids and tonsils, but also nonsurgical alternatives such as continuous positive air pressure, anti-inflammatory agents and oral appliances (OAs). Hence the therapeutic interventions that are directed at the site of airway obstruction in the maxillofacial region are within the scope of dentistry.
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