We report on the use of three ''cold'' atmosphericplasma(CAP) devices in treating model nails that have been coated on the backsideofthe nail with either Escherichia coli (E. coli)bacteria or Trichophyton rubrum (T. rubrum)f ungus. We tested ah elium plasma jet; as urface microdischarge plasma device; and afl oating electrode dielectric barrierd ischarge. All of the devices, acting through themodel nail, showed significant log reductions of bacterial and fungalt argets in several tens of minutes. CAP technology appears to offer promise as as afe, effective, and inexpensive therapy for fungal nail infection treatment.

Front Cover: 10% of the world's adult population has a fungal nail infection. Our findings demonstrate that cold atmospheric plasma (CAP) can penetrate a nail‐like barrier and kill underlying bacteria and fungus within minutes of treatment. While more testing and development needs to be done, CAP offers the promise of a safe and effective therapy for fungal infections of the nail and perhaps other tissues as well. Further details can be found in the article by Z. Xiong et al. http://doi.wiley.com/10.1002/ppap.201600010.