Introduction: Toxoplasma gondii and cytomegalovirus (CMV) are pathogens associated with congenital anomalies. Methods: Serum was collected from 79 reproductive-age women and tested for IgM and IgG antibodies to T. gondii and CMV. Results: Seropositivity for T. gondii was detected in 24.1% of women and CMV in 96.2%. High seropositivity for CMV was found for all ages. The highest seropositivity for T. gondii was observed among older participants. Conclusions: T. gondii remains an important pathogen owing to low seropositivity.

Aims: The objectives of this study were to find out whether and to what extent Actinomyces neuii is pathogenic to humans in terms of causing invasive infections and to ascertain the most appropriate and effective antibiotic therapy against this bacterium. Material and method: This study was designed as a systematic review article. MEDLINE, Google Scholar, SCIndex, Cochrane database of published clinical trials - Central and Clinicaltrials.gov databases were systematically searched for primary case reports or case series describing invasive infection with Actinomyces neuii. Results: A literature search identified 23 studies that met the inclusion criteria, describing cases of patients with an invasive infection caused by Actinomyces neuii. It was found that A. neuii could cause endocarditis, endophthalmitis, osteomyelitis, pleural empyema, soft tissue abscesses, neonatal sepsis, ventriculoperitoneal shunt infections and periprosthetic tissue infections. The most prescribed antibiotics for the treatment of Actinomyces neuii infections were amoxicillin and vancomycin (n = 10; 12.3%), followed by penicillin (n =9; 11.1%), gentamicin (n = 6; 7.4%), ampicillin (n = 5; 6.2%) and ceftazidime (n = 4; 4.9%). Antibiotic treatment of infections caused by A. neuii was followed by clinical improvement or complete cure of all patients, with no recorded deaths. Conclusion: A. neuii has a relevant pathogenic potential to cause invasive infections of various organs and tissues, especially in immunocompromised individuals of any age. For the treatment of mild infections caused by this bacterium, the antibiotics of choice are penicillin or amoxicillin, while vancomycin should be used to treat severe infections caused by Actinomyces neuii.

Uvod: Toxoplasma gondii je jedan od uzročnika iz grupe TORCH infekcija koje su najčešće povezane sa kongenitalnim anomalijama. Cilj: Definisanje faktora rizika za infekciju Toxoplasmom gondii kod žena u reproduktivnom periodu na teritoriji severne Kosovske Mitrovice kao i određivanje seroprevalence Toxoplasma gondii infekcije prenatalnim skriningom trudnica i žena u reproduktivnom periodu. Materijal i metode: Studija preseka je obuhvatila 49 trudnica i žena u reproduktivnom periodu. Praćena je trudnoća, ili su pak lečene u Ginekološko-akušerskom odeljenju Zdravstvenog centra u Kosovskoj Mitrovici. Starost, mesto stanovanja, obrazovanje, ginekološka istorija i izloženost potencijalnim faktorima rizika povezanih sa Toxoplasma infekcijom prikupljeni su upitnikom.Serumi su testirani na prisustvo IgM i IgG antitela na T. gondii ELISA testom po standardnom protokolu proizvođača (Euroimmun, Luebeck, Nemačka). Rezultati: Našei spitivanje je pokazalo da su 32 ( 65,3 % ) testirane žene seronegativne, a 17 (34,7 % ) žena je seropozitivno. Nešto značajniju seropozitivnost našli smo kod žena koje dolaze u kontakt sa zemljom (42,9%) u odnosu na žene koje ne dolaze u kontakt (23,8%). Korišćenje nedovoljno termički obrađenog mesa u ishrani nije pokazalo uticaj na seropozitivan status ispitanica, naime daleko veći procenat ispitivanih žena (75,5%) ne koristi u ishrani nedovoljno termički obrađeno meso. Čak 93,3% ispitanica negira kontakt sa mačkom. Seropozitivnost se sa godinama starosti povećavala. Zaključak: Seroprevalenca na Toxoplasma gondii infekciju kod žena u generativnom periodu na teritoriji severne Kosovske Mitrovice nije velika, te postoji veća šansa za sticanjem primarne infekcije toksoplazmom u trudnoći, posebno kod žena koje dolaze u kontakt sa zemljom.

Introduction/Aim: Pleural effusions are rarely seen on computerized tomography (CT) or radiography (X-ray) images of the chest, in coronavirus disease of 2019 (COVID-19). When present, they usually occur late in the course of the disease; they are mostly unilateral but can also be bilateral, and are absorbed after two days. Studies have also shown that pleural effusions occur primarily in the elderly and individuals with underlying respiratory disease. The incidence of respiratory failure and acute respiratory distress syndrome, as well as the mortality rates are higher in patients with pleural effusion than in patients without it. Our aim is to report a case that is different from the most commonly described cases in available literature. Patient presentation: We present a 49-year-old, comorbidity-free COVID-19 patient, who developed pleural effusion on the 10th day of hospitalization. The pleural effusion was unilateral and did not appear on a repeat lung radiography after four days. Except an elevated platelet count, the blood count parameters were in the reference ranges, while the value of CRP was slightly elevated. The patient was discharged with a good general health status, after 16 days of hospitalization. Conclusion: This case provides insight into the course and prognosis of the COVID-19 disease that is different from what has been reported in previously published papers and shows that pleural effusions do not occur only in elderly patients with comorbidities and a severe clinical presentation of the COVID-19 infection.

Uvod. Infekcije urinarnog trakta jedna su od najčešćih infekcija kod male dece. Febrilna stanja kod male dece, bez specifičnih kliničkih simptoma i znakova, često su posledica ITU. Obično se kasnije dijagnostikuju i leče. Najčešći uzročnik IUT je Escherihia coli. Glavni problem u lečenju IUT je sve veća rezistencija na antibiotike. Cilj rada. Da se ukaže na sve učestaliju rezistenciju na antibiotike i da se uporedi učestalost u ispitivanim periodima. Materijal i metode. Sprovedena je retrospektivna studija u periodu od 2010-2015.godine. Uzorci urina za mikrobiološki pregled, uzeti su pre uključivanja antibiotika. Statistička analiza obavljena je u SPSS softveru. Rezultati.U našem istraživanju nadjeno je 183 pacijenta sa dijagnozom IUT. Nešto u većem procentu bili su zastupljeni pacijenti ženskog pola. Najveći procenat rezistencije nadjen je na Ampicilin u našim rezultatima u vremenskom intervalu od 5.godina, nadjen je pad rezistencije na Amoxicilin i Amoksiklav. Diskusija. Naši rezultati, pokazali su veliku sličnost sa radovima na istoj temi, gde je Escherihia coli najčešći uzročnik IUT kod male dece. IUT zastupljenije su kod ženske populacije. Zaključak.Bitno je kontinuirano praćenje zastupljenosti urinarnih infekcija, kao i njihove osetljivosti na antimikrobne lekove, zbog sve veće prisutnosti rezistencije bakterija na postojeće antibiotike. Ključne reči: deca, infekcije urinarnog trakta, rezistencija, antibiotik.