cigarette smoking (based on smoking rates in a cross-sectional survey) did not influence the estimates. Conclusions While the results of this analysis did not reach statistical significance, they provide evidence supporting previous studies showing a risk of COPD associated with MWF exposure. The hazards presented are likely to be underestimates of the true association between COPD and MWF, due to the healthy worker effect. Objectives Exposure to silica dust is a health hazard in the ceramic industry. We studied cancer, mortality and acute myocardial infarction (AMI) among workers at a Swedish porcelain factory. 0225Method Annual average of exposure levels were estimated from 436 personal measurements of respirable crystalline silica dust (RCS) from 1971-2006. We investigated mortality, incidence of cancer, and first time event of AMI in men and women employed for at least one year at the factory in 1958-2009. We also studied the effect of latency, duration and cumulative exposure.Results RCS-levels among highly exposed workers were five times higher than the OEL and ten times higher in the early 1970s as in 2000.We found a non-significant elevated risk for lung cancer, (SIR 1.39; 95 % CI 0.79-2.25) and a significant elevated risk of squamous cell carcinoma in men (SIR 2.37; 1.02-4.66).Mortality from respiratory diseases was increased (SMR 1.75; 1.22-2.44), especially in men (SMR 1.86; 1.22-2.70). Among women, the risk for mortality from diseases of the circulatory system and incidence of AMI was elevated but not statistically significant. We found no dose-response relationship. There were eight cases of silicosis, and seven appeared with more than 30 years latency. Conclusions The increased risk for lung cancer and mortality from respiratory diseases was expected in view of the well-documented harmful effects of RCS. The tendency among women for increased mortality from diseases of the circulatory system and an increase in the incidence of AMI should be investigated in further studies. Objectives Increased research shows that perceived discrimination adversely affects physical and psychological health. Even though discrimination or concealed racism is an important characteristic of the Chilean society, which can be confirmed historically, it is not perceived as an important social problem for mainstream Chile. This paper aims to estimate the prevalence rate of workplace perceived discriminatory experience (WPDE) and its association with self-rated health status in the Chilean workforce Method Data from the first national survey on employment, work, and health in Chile. Study population of 9720 selected by multistage random sampling drawn to be representative of the entire working population. Study participants were asked about their WPDE (multiple questions) and general self rated health status (one question). Adjusting by demographic and socioeconomic factors, multivariable Poisson-log generalised linear mixed models were used to estimate the association between WPED and self-rated health. Results Approximatel...

Radiologists are intensive computer users as they review and interpret radiological examinations using the Picture Archiving and Communication Systems (PACS). Since their computer tasks require the prolonged use of pointing devices, a high prevalence of Musculoskeletal Disorders (MSDs) is reported. The first phase of this study involved conducting a Cognitive Work Analysis in conjunction with a Participatory Ergonomics approach to perform a total work system analysis. We also conducted an ergonomic survey as well as collected computer use data, specifically for the mouse and keyboard. The goal of the study was to reduce the physical exposures for radiologists. This paper presents Phase I results describing the analyses and redesign process of the radiologists tasks, training design, computer use, and selected survey results.

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number of flights per day (adjusted OR 2.0, 95% CI 1.2-3.3 for 3+ versus 1 flights/day, p trend = 0.007) and fewer time zones crossed per flight (adjusted OR 2.0, 95% CI 1.0-3.7 for 0 vs. 2 + time zones/flight, p trend = 0.04) were associated with a higher rate of endometriosis. Conclusions The rate of endometriosis increased with number of flights and decreased with time zones crossed, which might be surrogates for exposures specific to flying a series of short flights during the workday. 0117 NONMALIGNANT DISEASE MORTALITY AMONG STYRENE, FIBREGLASS, AND WOOD DUST EXPOSED WORKERS IN THE REINFORCED PLASTIC BOATBUILDING INDUSTRYAlysha Meyers, Steve Bertke, Avima Ruder. National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA 10.1136/oemed-2014-102362.40 Objectives To further evaluate the association of styrene, fibreglass, and wood dust exposure with non-malignant diseases, we extended follow-up through 2008 for 5203 workers exposed to styrene, fibreglass, and wood dust between 1959 and 1978 at two boat building plants.Method We used a person-years analysis program, LTAS.NET to compute standardised mortality ratios (SMRs) using Washington State and U.S. rates, standardised rate ratios (SRRs), and 95% confidence intervals. SMRs were stratified by exposure category (low or high) and duration of employment category (≤ 1 year, 1+ years). Results Overall, 1206 nonmalignant deaths occurred (WA SMR 1.14, CI 1.08-1.21), with excess mortality for chronic obstructive pulmonary disease (COPD) overall (n = 112, WA SMR 1.61, CI 1.32-1.93), and among 2063 workers highly exposed to styrene and fibreglass (n = 39, WA SMR 2.37, CI 1.69-3.25). Results were similar using U.S. mortality rates. Workers employed for less than one year had statistically significant increased mortality from several lifestyle-related outcomes (alcoholism, ischaemic heart disease, cirrhosis, accidental poisoning and homicide). Conclusions The excess COPD mortality in this cohort is difficult to interpret. Recent reports associate styrene/fibreglass reinforced plastic manufacturing with another respiratory diseasebronchiolitis obliterans. Based on a review of COPD death certificates, bronchiolitis obliterans does not appear to be a contributing factor for excess COPD mortality. The COPD excess in this study points to a need for an in-depth investigation of respiratory disease and occupational styrene exposure. Short term worker results are consistent with other occupational cohort studies. Objectives We investigated associations between nursing occupational exposures and menstrual cycle regularity and cycle length. 0119Method Cross-sectional data were collected in 2010-2012 from 6309 nurses aged 21 to 45 from the Nurses' Health Study 3. We used multivariable regression modelling to analyse the associations between occupational exposures and prevalence of irregular cycles and long and short cycle lengths. Results Cycle length was recorded as <21 days (1.5%), 21-25 days (15.6%), 26-31 days (69.7%), and 32-50 days (13.2%). In additio...

Very few studies considered the movement constraints imposed by the computer workstation during office computer work. The impact of computer workstation on user's muscle and joint coordination is not yet understood. This study examined three workstation configurations (sitting and standing with elbow desk height, and sitting with elevated desk) and analyzed their corresponding posture, muscle effort and inter-joint and muscle coordination. We found that sitting computer workstation with an elevated desk associated with more non-neutral postures and increased muscle load, particularly on the shoulders. Properly set up sitting and standing workstations resulted in similar median values for postures and muscle loads, but standing workstation allowed for greater muscle dynamic ranges and could be beneficial for short duration mouse tasks. Identifying effects of non-optimal configurations can lead to interventions to help decrease risks of developing musculoskeletal disorders.