Introduction: Stroke (Stroke) affects 15 million people annually, causing the death of 6.7 million. It is considered the predominant neurological disease in clinical practice, which brings neurological deficits such as total or partial paralysis of the hemibody (hemiparesis and hemiplegia), sensory, cognitive and visual impairment. In addition to impairing the performance of activities of daily living, the physical disabilities generated, decline the autonomy and independence of the individual, thus, physiotherapeutic assistance of paramount importance for rehabilitation, reversal, or minimizing the sequelae caused by stroke. Objective: to analyze the effects of functionality and quality of life on post-stroke patients. Method: this is a quantitative study, with a descriptive approach, carried out in an Integrated Continuous Care unit in the state of Mato Grosso do Sul (MS), with patients for stroke victims. Results: the research had a total of 21 participants, 21 (100%), with ages varying from 24 to 65 years old, being 62% male and 91% predominantly stroke. Based on the data, it was possible to observe that 81% of patients at the beginning of their hospitalization had some degree of dependence before any intervention of physiotherapy, or other professionals from the multiprofessional team, with 38% having a degree of severe or total dependence, only 4 patients (19%) were independent after being victims of Stroke. However, at hospital discharge 58% of the patients became completely independent, only 19%, corresponding to 4 patients, of the total surveyed, still had total or severe dependence, 81% of the patients achieved some gain in their clinical condition during hospitalization that corroborated in greater independence and autonomy. Conclusion: individuals affected by stroke have sequelae that corroborate the decline in the quality of life functionality, since the two are interconnected, results of risk factors that may be delineating a new profile of this population composed of individuals under 60 years old, predominantly male.