This paper looks to review the literature surrounding ‘What Works’ with women who are in, or at risk of entering the Criminal Justice System (CJS) and what approach practitioners should take to working with these women. The literature highlights the differing needs and complexities of women compared to their male counterparts. The importance of adopting a gender-responsive and trauma-informed approach to working with women is discussed. The literature surrounding effective interventions and the importance of promoting a positive self-identity are also reviewed along with the importance of staff wellbeing and resilience to effective practice. Recommendations for training of practitioners working with women who are in, or at risk of entering the CJS are made.