Traumatic brain injury (TBI) is a silent epidemic. Mild traumatic brain injury
(mTBI) causes brain injury that results in electrophysiologic abnormalities
visible on electroencephalography (EEG) recordings. The purpose of this brief
review was to discuss the importance of EEG findings in traumatic brain injury.
Relevant articles published during the 1996-2016 period were retrieved from
Medline (PubMed). The keywords were in English and included "traumatic brain
injury", "EEG" and "quantitative EEG". We found 460 articles, analyzed 52 and
selected 13 articles. EEG after TBI shows slowing of the posterior dominant
rhythm and increased diffuse theta slowing, which may revert to normal within
hours or may clear more slowly over many weeks. There are no clear EEG or
quantitative EEG (qEEG) features unique to mild traumatic brain injury. Although
the literature indicates the promise of qEEG in reaching a diagnosis and
indicating prognosis of mTBI, further study is needed to corroborate and refine
these methods.
Objective: We evaluated quantitative EEG measures to determine a screening index to discriminate Alzheimer’s disease (AD) patients from normal individuals.Methods: Two groups of individuals older than 50 years, comprising a control group of 57 normal volunteers and a study group of 50 patients with probable AD, were compared. EEG recordings were obtained from subjects in a wake state with eyes closed at rest for 30 min. Logistic regression analysis was conducted.Results: Spectral potentials of the alpha and theta bands were computed for all electrodes and the alpha/theta ratio calculated. Logistic regression of alpha/theta of the mean potential of the C3 and O1 electrodes was carried out. A formula was calculated to aid the diagnosis of AD yielding 76.4% sensitivity and 84.6% specificity for AD with an area under the ROC curve of 0.92.Conclusion: Logistic regression of alpha/theta of the spectrum of the mean potential of EEG represents a good marker discriminating AD patients from normal controls.
This article presents the recommendations on the pharmacological treatment employed in traumatic brain injury (TBI) at the outpatient clinic of the Cognitive Rehabilitation after TBI Service of the Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil. A systematic assessment of the consensus reached in other countries, and of articles on TBI available in the PUBMED and LILACS medical databases, was carried out. We offer recommendations of pharmacological treatments in patients after TBI with different symptoms.
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