PurposeFor adolescents and young adults (AYAs), the impact of a cancer diagnosis and subsequent treatment is likely to be distinct from other age groups given the unique and complex psychosocial challenges of this developmental phase. In this review of the literature, we report the health-related quality of life (HRQoL) issues experienced by AYAs diagnosed with cancer and undergoing treatment.MethodsMEDLINE, EMBASE, CINAHL, PsychINFO and the Cochrane Library Databases were searched for publications reporting HRQoL of AYAs. Issues generated from interviews with AYAs or from responses to patient reported outcome measures (PROMs) were extracted.Results166 papers were reviewed in full and comprised 72 papers covering 69 primary studies, 49 measurement development or evaluation papers and 45 reviews. Of the 69 studies reviewed, 11 (16%) used interviews to elicit AYAs’ descriptions of HRQoL issues. The majority of the PROMs used in the studies represent adaptations of paediatric or adult measures. HRQoL issues were organised into the following categories: physical, cognitive, restricted activities, relationships with others, fertility, emotions, body image and spirituality/outlook on life.ConclusionThe HRQoL issues presented within this review are likely to be informative to health care professionals and AYAs. The extensive list of issues suggests that the impact of a cancer diagnosis and treatment during adolescence and young adulthood is widespread and reflects the complexities of this developmental phase.

This study examined 131 U.S. middle class early, middle, and late adolescents' (M age ϭ 12. 74, 15.81, and 20.40 years, respectively) narratives regarding experiences of disclosure, concealment, and lying to parents and responses to direct probes about lessons learned about self and parents. The thematic content focused primarily on routine activities and peer experiences, and to a lesser extent, romantic issues, risky or delinquent behavior, and academic achievement, with few content differences across narrative types. Greater psychological elaboration in narratives and, when directly probed, more evidence of psychological growth and positive lessons about parents, were observed when teens disclosed than concealed or lied. There was less factual elaboration when youth narrated about concealment than disclosure or lying, particularly among early adolescent males as compared to older males and same-age females. Narrative coherence increased with age and was greater in females' than males' lying narratives. Thus, adolescents learn different lessons from disclosing, concealing, and lying, with varying implications for the development of self, identity, and moral agency.

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