TiO is a common inorganic filter used in sunscreens due to its photoprotective effect on the skin against UV radiation. However, the use of this kind of material in cosmetics is limited by its inherent photocatalytic activity. It is known that coating on TiO surface can improve some features. Although, many of the methodologies used for this purpose are still laborious and time-consuming. Thus, this work reports a novel, easy, cheap and fast strategy to coat TiO particles by using a sonochemistry approach, aiming to decrease photocatalytic activity and to enhance colloidal stability. For this proposal, SiO, AlO, ZrO and sodium polyacrylate (PAANa) were used to tune the surface of commercial TiO particles and they were applied in a sunscreen formulation. The samples were characterized by XRPD, FT-IR, DLS, EDS, SEM and TEM. The photocatalytic activity and UV-shielding ability were also evaluated. The sunscreen formulations were prepared and characterized by zeta potential, DLS, and Sun Protection Factor (SPF). FT-IR, EDS, and charge surface of the particles confirmed the success of the sonochemistry coating. Additionally, TiO@AlO, TiO@SiO and TiO@PAANa show a lower photocatalytic activity than original TiO with similar UV-shielding ability. The sunscreens produced with the coated TiO have similar SPF to the one with commercial TiO. Specifically, the sunscreen with TiO@PAANa shows an increase in colloidal stability. Herein, the incorporation of the sonochemical-coated TiO particles in sunscreen formulations may produce sunscreens with better aesthetic appearance and a greater health security due to its lower free radicals production.

PURPOSE:To study the anti-inflammatory actions of electroacupuncture (EAc) on an experimental colitis model in mice. METHODS:Thirty-eight male Swiss mice, divided in five groups, were subjected to induction of colitis by TNBS in 50% ethanol.Saline (SAL) and ethanol (ETNL) groups served as controls. TNBS+EAc and TNBS+ dexamethasone subgroups were treated with EAc 100Hz and dexamethasone (DEXA) 1 mg/Kg/day, respectively. After three days, a colon segment was obtained for quantification of myeloperoxidase (MPO) activity, immunohistochemistry for iNOS, malondialdehyde (MDA) and cytokines (IL-1β and IL-10). RESULTS:Neutrophilic activity, assayed as MPO activity, was significantly higher in the TNBS colitis group than that in the saline control group. TNBS+EAc group showed suppression of IL-10 in the colon. EAc treatment significantly reduced the concentration of MDA and the expression of iNOS, as compared to the other groups. CONCLUSION: Electroacupuncture 100Hz applied to acupoint ST-36 promotes an anti-inflammatory action on the TNBS-induced colitis, mediated by increase of IL-10 and decrease of iNOS expression.

No abstract

No abstract

O presente artigo tem por objetivo apresentar um estudo comparativo das louças encontradas em áreas de ocorrência arqueológica na região metropolitana de Curitiba. As ocorrências foram identificadas durante trabalhos de Acompanhamento Arqueológico na área de instalação de dois condomínios residenciais, o Condomínio Madison na cidade de Campo Largo e o Condomínio Benvenue no município de Almirante Tamandaré. Esse trabalho busca demonstrar o potencial informativo dos artefatos coletados durante os trabalhos de arqueologia preventiva, bem como visa contribuir com os estudos acerca da louça de fabricação nacional tendo em vista que essa região foi uma das pioneiras na produção industrial desses objetos.