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In the past few decades, there has been rapid growth in quantity and variety of healthcare data. These large sets of data are usually high dimensional (e.g. patients, their diagnoses, and medications to treat their diagnoses) and cannot be adequately represented as matrices. Thus, many existing algorithms can not analyze them. To accommodate these high dimensional data, tensor factorization, which can be viewed as a higher-order extension of methods like PCA, has attracted much attention and emerged as a promising solution. However, tensor factorization is a computationally expensive task, and existing methods developed to factor large tensors are not flexible enough for real-world situations. To address this scaling problem more efficiently, we introduce , a distributed, scalable, and sparse tensor factorization method fit through stochastic gradient descent. offers three contributions: (1) Scalability: it employs a block partitioning and parallel processing design and thus scales to large tensors, (2) Accuracy: we show that our method can achieve results faster without sacrificing the quality of the tensor decomposition, and (3) FlexibleConstraints: we show our approach can encompass various kinds of constraints including l2 norm, l1 norm, and logistic regularization. We demonstrate ’s capabilities in two real-world use cases. In the first, we use Google searches for flu-like symptoms to characterize and predict influenza patterns. In the second, we use to extract clinically interesting sets (i.e., phenotypes) of patients from electronic health records. Through these case studies, we show has the potential to be used to rapidly characterize, predict, and manage a large multimodal datasets, thereby promising a novel, data-driven solution that can benefit very large segments of the population.

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Machine learning methods allow us to make recommendations to users in applications across fields including entertainment, dating, and commerce, by exploiting similarities in users' interaction patterns. However, in domains that demand protection of personally sensitive data, such as medicine or banking, how can we learn such a model without accessing the sensitive data, and without inadvertently leaking private information? We propose a new federated approach to learning global and local private models for recommendation without collecting raw data, user statistics, or information about personal preferences. Our method produces a set of prototypes that allows us to infer global behavioral patterns, while providing differential privacy guarantees for users in any database of the system. By requiring only two rounds of communication, we both reduce the communication costs and avoid the excessive privacy loss associated with iterative procedures. We test our framework on synthetic data as well as real federated medical data and Movielens ratings data. We show local adaptation of the global model allows our method to outperform centralized matrix-factorization-based recommender system models, both in terms of accuracy of matrix reconstruction and in terms of relevance of the recommendations, while maintaining provable privacy guarantees. We also show that our method is more robust and is characterized by smaller variance than individual models learned by independent entities.