No abstract

Backgroundthe measurement of the spaces of occupation of irregular objects in the context of fractal geometry has had some applications at a cellular morphometric level, where characterizations of normality and disease have been established. The objective of the present study is to apply a fractal methodology to characterize images from cervical colposcopy.Materials and methodsa mathematical and geometrical characterization of 67 cell samples was performed by measuring cellular fractal characteristics through the Box‐Counting method, being nine normal, eight low‐intraepithelial lesions, 16 high‐intraepithelial lesions, eight carcinomas in situ, 20 squamous cell carcinomas and six endocervical carcinomas.Resultsthe values of fractal dimension of the nuclear and cytoplasmic borders with respect to the totality varied between 0.719 to 1128 and 0.81 to 1024 while the occupation spaces in the 2 pixels grid were between 293 to 1606 and 64 to 693 respectively and in the 4 pixels grid oscillated between 153 to 894 and 36 to 361, respectively. Exocervical cells values had sensitivities between 78.3% to 100% in order to differentiate them from different types of cervical lesions.Conclusionsaccording to the results obtained, the mathematical values found are suggestive of being able to differentiate between normality and some colposcopy‐guided cervical biopsy lesions.

El síndrome de la bolsa de orina púrpura es una entidad poco frecuente, con una prevalencia hasta de un 8% en pacientes con catéteres permanentes crónicos por más de 2 años. Esta condición se presenta en portadores de sonda vesical, siendo su principal signo clínico la aparición de orina de color púrpura, debida a la producción de sulfatasas y fosfatasas por enterobacterias. Se presenta un caso de una mujer de 63 años con diagnóstico de vejiga neurogénica, antecedente de enfermedad cerebrovascular y secuelas motoras debidas a neoplasia cerebral, quien consultó por presentar el color característico, con síntomas de infección del tracto urinario inferior. Se trató con nitrofurantoína y tuvo normalización del color urinario al quinto día de tratamiento. El diagnóstico de este síndrome implica un reto para el médico, y deben detectarse los factores de riesgo para proveer un adecuado manejo antimicrobiano y evitar el uso de recursos diagnósticos innecesarios.