Introduction: Chronic primary osteomyelitis (CPO) is a rare disease, defined as a chronic inflammatory process involving cortical and medullary bone. In the maxillofacial region, it mainly affects the mandible, with a predilection for females in a wide age range, with unknown etiology or defined treatment protocol. Objective: The objective of this article is to report a case of the rare disease Chronic Primary Osteomyelitis, focusing on its clinical, radiographic, and histopathological characteristics, and to discuss the nomenclature for differential diagnosis while comparing with other osteomyelitis. Case Report: MLP patient, 53 years old, female, leukoderma, was admitted at the Maxillofacial Surgery and Traumatology Service of the University Hospital of USP referred from another service and reported of severe pain and swelling in the face for approximately 1 .5 year. On clinical examination, he presented edema 1+/4+ in the lower third of the right hemiface, sensitive to palpation, trismus, lower lip paresthesia, no evidence of infectious odontogenic focus, increased volume or intraoral secretion. The patient was submitted to an incisional biopsy, computed tomography and scintigraphy, which showed an sclerotic pattern and increased uptake in the mandible, respectively. After months of antibiotic therapy with no results, the patient was initially submitted to 20mg of Prednisone with regression up to 5mg and two doses of 60mg of Pamidronate which resulted in remission of pain, edema and trismus. Until the publication of this article, the patient had no recurrence of the symptoms, totalizing 6 years of follow up. Conclusion: CPO is a rare and challenging diagnosis disease. Prednisone was effective to edema and trismus decreasement and Pamidronate for pain control, however more studies are necessary to determine a definitive treatment for this condition.

Introduction: The COVID-19 pandemic has changed the routine of dental care all over the world due to the high risk of contamination by handling body fluids and aerosol production. Biosafety measures were intensified, and dental appointments were restricted to emergencies. In Oral Medicine, the early diagnosis of oral cancer is one of the main urgencies. Objective: The aim of this article is to report a case of oral cancer that was diagnosed during social isolation through a digital messaging platform, in a patient with history of oral potentially malignant disorder. Case Report: The present case report refers to the diagnosis of oral squamous cell carcinoma in an 83-year-old Asian woman with a history of oral potentially malignant disorder. The aforementioned malignant lesion was suspected during a remote consultation using the WhatsApp platform. After the telephone consultation regarding the possible diagnosis, the patient sought care at the referral hospital and underwent clinical examinations, laboratory testing, computed tomography scans and an incisional biopsy to confirm the diagnosis and begin with adequate treatment. Conclusion: The need to mitigate the spread of SARS-CoV-2 prompted the need for and implementation of Teledentistry resources in all fields, including Oral Medicine. Despite being rare, malignant lesions can be diagnosed, as was done in the present report and Oral Medicine plays a crucial role in early diagnosis.