Objective: Nelson syndrome (NS) is a rare clinical disorder that can occur after total bilateral adrenalectomy (TBA), performed as a treatment for Cushing disease. NS is defined as the accelerated growth of an adrenocorticotropic hormone-producing pituitary adenoma. Our objective is to describe a case of NS and discuss it based on existing knowledge of this syndrome. Methods: We describe the case of a woman diagnosed with NS at our facility in the Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran and review published cases of NS. Results: The patient, a 35-year-old woman with Cushing disease, had been diagnosed in 2006 at the endocrinology department in the Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran. In 2007, a laparoscopic TBA was performed, and 2 years later, she presented with hyperpigmentation and adrenocorticotropic hormone levels of up to 11 846 pg/mL. NS was suspected, and as magnetic resonance imaging showed macroadenoma, transsphenoidal surgery was performed. The patient remained asymptomatic until 2012, when she presented with a right hemicranial headache, photophobia, and phonophobia. A fresh magnetic resonance imaging was performed, which documented tumor growth. She was referred to the Instituto Nacional de Neurologia y Neurocirugia, where she underwent surgery. Conclusion: NS develops as a complication of TBA, which is used as a treatment of Cushing disease. The main treatment is surgery and radiotherapy.
La atención médica durante la pandemia de COVID-19 representó grandes retos éticos y bioéticos. Entre los más complejos estuvieron la distribución de recursos sanitarios y la consecuente selección de pacientes para atender sus posibilidades de supervivencia, y la incorporación de los cuidados paliativos, el consentimiento informado y las voluntades anticipadas a los protocolos de actuación y admisión de pacientes. Desde criterios utilitaristas, que pugnaban únicamente por el valor social y la utilidad, hasta criterios personalistas basados en los principios de subsidiariedad y solidaridad, la atención de los pacientes se volvió apremiante sin importar su condición. En este artículo se aborda el dilema sobre los criterios de distribución que fue profundizándose a lo largo de este tiempo, y se propone que la protección de la salud, siendo un derecho humano universal, no puede pasar inadvertida en pacientes con pronósticos desfavorables, proponiéndose la incorporación de cuidados paliativos en la atención médica.
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