Venipuncture is a common medical procedure. The use of augmented reality-based assistive devices can improve the first puncture success rate in patients with poor vascular filling. In order to improve the image rendering quality and speed of auxiliary equipment, this study develop a two-dimensional matched filtering algorithm on a Field Programmable Gate Array (FPGA) in a near-infrared vein imaging system, which use parallel processing to offer real-time response and is designed as a small handheld portable device. A customized dorsal hand vein image library with 200 images captured from 120 participants is used to analyze the effects of convolution kernel parameters and exposure time on vascular imaging with different depths, and the correlation model between these parameters and vascular depth are constructed. We use the Tenengrad, variance, Laplace smoothness and standard deviation as evaluation indicators, and compare our algorithm with three other related studies. Experimental results show that the rendering quality of our proposed algorithm is significantly higher than other algorithms. In addition, the rendering speed of our algorithm can reach 66 fps, which is twice faster than the current fastest algorithm.
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