Extreme learning machine (ELM) has become a popular topic in machine learning in recent years. ELM is a new kind of single-hidden layer feedforward neural network with an extremely low computational cost. ELM, however, has two evident drawbacks: 1) the output weights solved by Moore-Penrose generalized inverse is a least squares minimization issue, which easily suffers from overfitting and 2) the accuracy of ELM is drastically sensitive to the number of hidden neurons so that a large model is usually generated. This brief presents a sparse Bayesian approach for learning the output weights of ELM in classification. The new model, called Sparse Bayesian ELM (SBELM), can resolve these two drawbacks by estimating the marginal likelihood of network outputs and automatically pruning most of the redundant hidden neurons during learning phase, which results in an accurate and compact model. The proposed SBELM is evaluated on wide types of benchmark classification problems, which verifies that the accuracy of SBELM model is relatively insensitive to the number of hidden neurons; and hence a much more compact model is always produced as compared with other state-of-the-art neural network classifiers.

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Oxalierpenes A and B (1 and 2), two unusual indole-diterpenoid derivatives, were obtained from the marine-derived fungus Penicillium oxalicum. The absolute configurations of 1 and 2 were elucidated by calculated TDDFT ECD and DP4plus methods. Oxalierpene A (1) represents the first indole-diterpenoid derivative with a five-membered ring of 4-hydroxy-5,5dimethyldihydrofuran-3-one as a side chain. Oxalierpene B (2) has a unique 6/5/6/5/5/6/6/5/5 ring system. Compounds 1 and 2 showed antiviral activity against the H1N1 virus and respiratory syncytial virus (RSV), with IC 50 values ranging from 2.8 to 9.4 μM.

Two Cd-based supramolecular coordination polymers, [Cd 3 (CzIP) 3 (DMF) 2 ] (1) and [Cd 2 (CzIP) 2 (DMF) 4 ] (2), were synthesized by using 5-(carbazol-9-yl) isophthalate (CzIP) as ligands. These two compounds exhibit multiple luminescence emissions; apart from fluorescence, time-and temperaturedependent ultralong phosphorescence (RTP) were also achieved under room conditions. Significantly, compound 1 has a long-lived afterglow of 0.93 s at 545 nm under ambient conditions. Compound 2 shows nearly pure white-light emission with CIE coordinates of (0.33, 0.33) via the dual emission of fluorescence and phosphorescence. It has come to our attention that it is the first example of a luminescent coordination polymer with singlephase white-light emission and color-evolution RTP. In addition, the long-lived RTP materials can be used in time-dependent anticounterfeiting and white-light-emitting diodes. Experimental and singlet and triplet state calculations indicate that both C−H•••π interaction and inter-and intramolecular charge transfer interactions could be beneficial to the emission of ultralong RTP.

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