No abstract

No abstract

Ultrasound-modulated optical tomography is a proiinising and noninvasive method for biomedical imaging. The advantage of this technology is its combination of optical contrast and ultrasonic resolution. In order to reconstruct the tissue imaging effectively and reliably,

Because it has the advantages of optical contrast and ultrasonic resolution, the ultrasound-modulated optical tomography becomes a new and promising method for biomedical imaging. The propagation of the light modulated by ultrasound in the tissue plays an important role in this new technique. We already proved that the modulated depth of the modulated light (Identical Modulated Depth, ignoring the background diffused light) was dependent on optical and ultrasonic properties of tissue within the ultrasound zoom, and didn't change in the propagation in the recent research. However, the modulation depth detected at the surface in experiment (Real Modulated Depth) differs from the Identical Modulated Depth, which includes the background diffused light. In Diffuse theory and experiments it is shown that the Real Modulated Depth is dependent on the propagation process of the diffused light. The relations to the Real Modulated Depth contributed by the tissue thickness, optical properties, etc. are figured out in this paper. So the Real Modulated Depth detected in the experiments should be transformed into the Identical Modulated Depth (a dominant parameter to imaging) by a set of iterated algorithm decoding. All these should contribute to the practical applications of ultrasound-modulated optical tomography.

In this presentation, several ultrasound-modulated optical phenomena in a tissue phantom were observed by a pulsed ultrasound transducer. Some factors affected the modulated signal value were studied including the changing of the experimental conditions such as the distance between the focused volume of ultrasound beam and the detector as well as the frequency of ultrasound transducer. The experimental results and the analysis suggest that a compositive parameter concerning the intensity of the modulated signal, namely the modulation depth which is a key parameter to measure the scattering property even as a sensor to indicate the glucose concentration.