Background: Due to the COVID-19 pandemic, in 2020, many employees were required to work from home (WFH). During this WFH period, some employees encountered health issues related to sprains and neck or back pain owing to poor working conditions at home. As the WFH trend may continue over a prolonged period, the underlying causes and solutions to ergonomic issues must be addressed to reduce injuries. This study aims to identify the ergonomic issues encountered when working from home and suggests several solutions to minimise these issues. Methods: A qualitative ethnographic methodology was adopted. This study used focus group discussion and the panellists were among experts from the fields of higher education, healthcare, human resources (HR), and ergonomics patient in Malaysia. The most common ergonomic issues identified were based on diagnoses and observations in previous studies. Results: The panellists agreed on ergonomics issues, comprising the use of unergonomic chairs, incorrect sitting postures, irregular arrangement of key objects, improper reach distances of the laptop/keyboard/mouse, poor desk designs, footrest absence, distortion/noise, poor lighting, and poor work environment. Over time, WFH ergonomics issues may lead to burnout, carpal tunnel syndrome or other cumulative trauma disorders, high blood pressure, and stress on the cervical spine and neck. The proposed solutions include a complete WFH ergonomics and wellness checklist for employees and employers, webinar sessions on WFH ergonomics, meet-up sessions with ergonomics or HR experts, workspace rentals for co-workers, implementation of the 20-20-20 rule and job-sharing practices, and the involvement of employers or the government in procuring ergonomic equipment for WFH employees. Conclusions: This is a preliminary study and the researchers are exploring the root causes of WFH ergonomics issues and proposed solutions. While previous studies have examined workplace ergonomics, this study focuses on WFH ergonomic issues and solutions during the ongoing pandemic.