The traditional product form design research usually starts from a single aspect such as aesthetics, ergonomics and Kansei engineering, and lacks the comprehensive consideration of multiple constraints. To solve this problem, a product form optimization design method oriented to aesthetics and ergonomics is proposed. First, based on the theory of computational aesthetics, a quantitative product form aesthetic index system is established. Using the entropy method to achieve the comprehensive evaluation of product form aesthetics. The ergonomic evaluation is carried out by measuring the difference between the standard values and the actual values of the design parameters. Then, taking the aesthetic and ergonomic evaluation as game players, a noncooperative game model is established, and the Nash equilibrium is solved to achieve product form optimization. Finally, We verify by experiments that this method can better realize the multifactor fusion design of the product.