Hydroxycinnamic acid compounds are an important source of antioxidants due to their ubiquitous occurrence in the plant kingdom and their characteristic activities. In this study, we compared the antioxidative and free radical scavenging activities of caffeic acid (CA), caffeic acid phenethyl ester (CAPE), ferulic acid (FA), ferulic acid phenethyl ester (FAPE), rosmarinic acid (RA), and chlorogenic acid (CHA) with those of α-tocopherol and BHT. In the Rancimat test, the addition of test compounds in lard significantly extended the induction time of lipid oxidation, and the activities in decreasing order were CA ∼ α-tocopherol > CAPE ∼ RA > CHA ≫ BHT > FA ∼ FAPE. When the lipid substrate was changed to corn oil, the effectiveness of antioxidants on the induction time was obviously decreased, and the potency order of antioxidants was changed to RA > CA ∼ CAPE ∼ CHA > α-tocopherol > BHT; FA and FAPE had no significant antioxidative effect in the corn oil system. The 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) scavenging activity of the test compounds was RA ≫ CAPE > CA > CHA > α-tocopherol > FA > FAPE > BHT. The effect on retarding oil-in-water emulsion oxidation was BHT > CA > CAPE > RA > FA > CHA > α-tocopherol > FAPE, and the incubation times to reach an absorbance of 0.4 by the ferric thiocyanate method were 14.4, 11.4, 8.6, 7.3, 6.4, 4.6, 4.2, and 2.8 days, respectively, with the value of the control around 1.3 days. Keywords: Antioxidants; caffeic acid; caffeic acid phenethyl ester; free radical scavenging activity; hydroxycinnamic acids
T he pulmonary interlobar fissures are important landmarks for pulmonary anatomy. They adopt a double membrane structure formed by invagination of the visceral pleura. The interlobar fissures are 1-3 mm thick and consist of the right oblique fissure (ROF), horizontal fissure (HF), and left oblique fissure (LOF) (1, 2). The recognition of pulmonary interlobar fissures and their variations is beneficial for identifying pulmonary lesion locations, evaluating disease progression, selecting surgical operations, and applying endoscopic therapy (3-5). With the constant development of imaging techniques, thin-section computed tomography (CT) can provide more detailed information regarding lung structure with respect to the anatomy (5-7). Multiplanar reformatting (MPR) (8) and maximal intensity projection (MIP) are reconstruction techniques based on a noninvasive methodology that detect pulmonary interlobar fissure variations. The results generated by these techniques highly resemble the results of an autopsy (8). In this study, the pulmonary interlobar fissures and their variations were investigated and analyzed by volumetric thin-section MPR and MIP images. MethodsThe study was approved by the institutional review board and the institutional ethics committee. A retrospective analysis was performed on CT scans of 862 adult subjects ( PURPOSEWe aimed to perform an imaging analysis of interlobar fissures and their variations using thin-section computed tomography (CT). METHODSVolumetric thin-section CT scanning was performed in 208 subjects. Interlobar fissures were observed on axial images, and reconstructed coronal and sagittal images were observed by multiplanar reformatting (MPR). The vessel distributions were verified by maximal intensity projection (MIP). On the axial images, the interlobar fissures were characterized by lines of hyperattenuation, bands of hyperattenuation, avascular zones, and mixed imaging. The interlobar fissures were divided into seven grades according to the percentage of defects over the entire fissure. RESULTSOn the axial images, of all interlobar fissures without avascular zones, 70.2% of the right oblique fissures (ROFs) and 94.2% of the left oblique fissures (LOFs) appeared as lines, and 83.2% of the horizontal fissures (HFs) appeared as bands. All of the interlobar fissures appeared as lines on the coronal and sagittal images. Of all cases, 17.8% showed fully complete interlobar fissures for all three fissures. Incomplete fissures included 41.3% of ROFs, 58.2% of HFs, and 45.2% of LOFs. In ROFs and LOFs, discontinuity was most frequently below 20%, while in HFs discontinuity was most frequently 41%-60%. The most common classification of incomplete interlobar fissures was a discontinuous avascular zone. CONCLUSIONIncomplete interlobar fissures are common variations of interlobar fissures. Techniques including volumetric thin-section CT, MPR, and MIP can assist in the diagnosis of incomplete interlobar fissures.
This paper presents a numerical study on the mechanical behavior of the jointed rocks around the underground opening. By comparing different obliquities and the different locations of the joint, its controlling effect on stability of surrounding rock is evaluated in terms of the shear stress distribution, displacement distribution and the plastic zone pattern, which are induced by underground excavation. The results clearly indicate that, the maximum shear stress occurs mainly near the corner of the opening and the joint plane. When the joint inclination angle is less than 60º, the maximum vertical displacements occur where the joint locates near the skewback. Once the joint inclination angle reaches at 75º, the maximum vertical displacements occur where the joint is through the cross section of the underground opening. The plastic zone reaches minimum at the joint inclination angle of 45º where the joint locates either near the skewback or near spandrel of the opening, while it reaches minimum at the joint inclination angle of 60º where the joint cuts through the cross section of the opening.
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