Anton-Babinski syndrome is a rare disease featuring bilateral cortical blindness and anosognosia with visual confabulation, but without dementia or any memory impairment. It has a unique neuropsychiatric presentation and should be highly suspected in those with odd visual loss and imaging evidence of occipital lobe injury. In the case discussed herein, a 90-year-old man presented with bilateral blindness, obvious anosognosia, and vivid visual confabulation, which he had had for 3 days. Brain computed tomography demonstrated recent hypodense infarctions at the bilateral occipital lobes. Thus, the patient was diagnosed with Anton-Babinski syndrome. Because of his age and the thrombolytic therapy during the golden 3 hours after ischemic stroke, the patient received aspirin therapy rather than tissue plasminogen activator or warfarin. He gradually realized he was blind during the following week, but died of pneumonia 1 month later. In the literature, it is difficult to establish awareness of blindness in patients with Anton-Babinski syndrome, but optimistically, in one report, a patient was aware of blindness within 2 weeks, without vision improvement. Our case illustrates that elderly patients with Anton-Babinski syndrome can partially recover and that 1 week is the shortest time for the establishment of awareness of blindness for sufferers without vision improvement.
Introduction: In the first three months of pregnancy, 23.8% of females experience migraines, and 63.6% have episodes of dizziness, with the most frequent symptom being (35.7%) vertigo. Therefore, vestibular migraine is expected to occur in pregnant women, yet studies in this regard are limited in the literature. We studied such a case in order to determine the safest treatment for patients with possible pregnancy. Case Presentation: The studied case was a 37-year-old female, who had a history of migraines. She had had vestibular migraines eight times since she was 29 years old. During the second attack, she had been conservatively treated with several anti-vertigo and anti-emetic medications. Because her menses was a little out of schedule, she receive pregnancy test, and to our surprise, the test showed positive results. Afterwards, she was transferred to an obstetric hospital for prenatal examinations and had follow-ups for ten months. Eight months after delivery, the third vestibular migraine occurred. Because of lactation, she did not take any medications; vertigo continued for half a day, and dizziness remitted over the following two days. Conclusions: Pregnancy is expected to occur together with vertigo in females of the childbearing age, even if they have been diagnosed with sterility. Any anti-vertiginous medication with teratogenic risk should be avoided if pregnancy is not completely excluded, antihistamine diphenhydramine (FDA class B) are recommended first for symptomatic control.
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