Antral follicle count (AFC) has been widely investigated for the prediction of clinical pregnancy or live birth. This study discussed the effects of AFC quartile levels on pregnancy outcomes combined with female age, female cause of infertility, and ovarian response undergoing in vitro fertilization (IVF) treatment. At present, many research about AFC mainly discuss its impact on clinical practice at different thresholds, or the analyses of AFC with respect to assisted reproductive technology outcomes under using different ovarian stimulation protocols. Factors that include ovarian sensitivity index, female age, and infertility cause are all independent predictors of live birth undergoing IVF/intracytoplasmic sperm injection, while few researchers discussed influence of female-related factors for clinical outcomes in different AFC fields.A total of 8269 infertile women who were stimulated with a long protocol with normal menstrual cycles were enrolled in the study, and patients were categorized into 4 groups based on AFC quartiles (1–8, 9–12, 13–17, and ≥18 antral follicles).The clinical pregnancy rates increased in the 4 AFC groups (28.25% vs 35.38% vs 37.38% vs 40.13%), and there was a negative association between age and the 4 AFC groups. In addition, female cause of infertility like polycystic ovary syndrome, Tubal factor, and other causes had great significance on clinical outcome, and ovarian response in medium (9–16 oocytes retrieved) had the highest clinical pregnancy rate at AFC quartiles of 1 to 8, 9 to 12, 13 to 17, and ≥18 antral follicles.This study concludes that the female-related parameters (female cause of infertility, female age, and ovarian response) combined with AFC can be useful to estimate the probability of clinical pregnancy.
The objective of this paper was to compare the effect of recombinant follicle-stimulating hormone (rFSH) and urinary follicle-stimulating hormone (uFSH) on pregnancy rates and live birth rates with the gonadotropin-releasing hormone
(
GnRH) antagonist protocol in China. This retrospective study was conducted from January 2014 through August 2017. Patients treated with uFSH had significantly higher levels of luteinizing hormone (3.79 mIU/ml vs. 3.09 mIU/ml) and progesterone (0.93 ng/ml vs. 1.16 ng/ml) on the day of human chorionic gonadotropin (HCG) administration, and they also had higher pregnancy rates (24.19% vs. 22.86%). There was no significant difference in the rate of live births. In the logistic regression results of the rFSH group, the pregnancy rate was positively correlated with the level of luteinizing hormone, with an odds ratio (OR) of 1.09 (95% confidence interval [CI]: 1.00–1.18; P = 0.048). In the uFSH group, the pregnancy rate was negatively correlated with the progesterone level on the day of HCG administration, with an OR of 0.47 (95% CI: 0.27–0.77; P = 0.004). Our research concluded that uFSH performed better than rFSH in terms of pregnancy rates when it was associated with the GnRH antagonist protocol. Meanwhile, no significant differences in the rate of live births were observed between the two groups.
With the progress of urbanization in China, the energy-saving renovation of a large number of existing buildings, especially old buildings, has become an important project for the green and low-carbon development of urban renewal. This paper takes the old brick school building in a university in Chengdu as an example. Through field research, the existing problems of the building are analyzed in detail in terms of building function, structure and appearance, and a detailed plan for functional upgrading, structural reinforcement and façade renovation is drawn up, taking into account the actual requirements and environmental status. In addition, solar photovoltaic technology is integrated into the renovation of the building’s pitched roof. Through modelling and analysis, the amount of solar energy captured by the photovoltaic roof is quantitatively simulated and the dynamic energy-saving potential of the renovation project under changing actual meteorological conditions is pre-evaluated. The preliminary results indicate that such green renovations can contribute to about 164,066 kWh annual solar energy collection and the self-use electricity from the PV roof accounts for 42–76% of total energy consumption, leading to about 60% building energy consumption conservation. The payback period of such a renovation program is assessed to be about 1.9 years, which is quite economically feasible considering the local energy tariff policy. This paper explores the feasibility and design direction of green and low-carbon renovation and upgrading of old buildings, which can provide a reference for the application of green and low-carbon renovation of local old buildings.
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