Nitrogen-containing compounds are ubiquitously found in the fields of organic chemistry, pharmaceuticals, agrochemicals, medicinal chemistry and functional materials. The C-H bond amination reaction is one of the most straightforward protocols in the C-N bond formation, showing "step" and "atomic" economy. As a catalyst for C-H amination reaction, copper exhibits its unique catalytic properties due to easily accessible oxidation states. The research progress of copper-catalyzed C-H amination in recent years is summarized. At the same time, reaction mechanisms are also briefly described in representative aminations to provide insights for the development prospects of highly practical and more environmentally benign processes.

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Construction of a carbon-nitrogen bond is one of the most prevalent operations in nature and organic synthesis. The resulting amino compounds are privileged structural fragments in natural products, pharmaceutical drugs,...

A new fluorinated anionic surfactant Cl(CF 2 ) 6 O(CF 2 ) 2 SO 3 N(C 2 H 5 ) 4 was prepared and characterized. The application of the fluorosurfactant allowed the fluoroalkylation to occur in the water without adding organic solvent. The addition of perfluoroalkyl iodides with olefins and alkynes under the initiation of Na 2 S 2 O 4 in water in the presence of the fluorosurfactant gave the corresponding adducts in good to excellent yields. The fluorosurfactant was suitable for a radical addition process.