During the COVID-19 quarantine period, mobile technologies have been greatly promoted to be used by students to assist their learning. Although mobile learning has been well researched, studies investigating rural school students' intentions were not enough. This study investigated rural secondary school students' mobile technology uptake and their perceptions of using mobile technologies in informal English learning during the COVID-19 epidemic. Results suggested Chinese rural school students held positive attitudes towards mobile assisted English learning, and they most tended to use smartphones, followed by portable electronic dictionaries, tablets and laptops in informal English learning. Rural secondary school students' behavioral intentions (BI) were significantly influenced by perceived usefulness (PU), facilitating conditions (FC) and attitude towards use (ATU) of mobile devices. Innovativeness (INNO) and perceived ease of use (PEU) did not significantly influence students' behavioral intentions. These factors explained 83.1% of variance of students' behavioral intentions. Based on the findings, the study offers suggestions that teachers, governments and educational policy makers take measures to pay attention to students' mobile learning in informal English learning.
The popular BFGS quasi-Newton minimization algorithm under reasonable conditions converges globally on smooth convex functions. This result was proved by Powell in a landmark 1976 paper: we consider its implications for functions that are not smooth. In particular, an analogous convergence result holds for functions (like the Euclidean norm) whose minimizers are isolated nonsmooth points.
Background. Men have a higher risk and earlier onset of cardiovascular diseases compared with premenopausal women. Hypertriglyceridemia is an independent risk factor for the occurrence of ischemic heart disease. Endothelial dysfunction is related to the development of ischemic heart disease. Whether sex differences will affect the circulating endothelial progenitor cells (EPCs) and endothelial function in hypertriglyceridemia patients or not is not clear. Methods. Forty premenopausal women and forty age- and body mass index (BMI)-matched men without cardiovascular and metabolic disease were recruited and then divided into four groups: normotriglyceridemic women (women with serum triglycerides level <150 mg/dl), hypertriglyceridemic women (women with serum triglycerides level ≥150 mg/dl), normotriglyceridemic men (men with serum triglycerides level <150 mg/dl), and hypertriglyceridemic men (men with serum triglycerides level ≥150 mg/dl). Peripheral blood was obtained and evaluated. Flow-mediated dilatation (FMD), the number and activity of circulating EPCs, and the levels of nitric oxide (NO), vascular endothelial growth factor (VEGF), and granulocyte-macrophage colony-stimulating factor (GM-CSF) in plasma and culture medium were measured. Results. The number and activity of circulating EPCs, as well as the level of NO in plasma or culture medium, were remarkably increased in premenopausal females compared with those in males both in the hypertriglyceridemic group and the normotriglyceridemic group. The EPC counts and activity, as well as the production of NO, were restored in hypertriglyceridemic premenopausal women compared with those in normal women. However, in hypertriglyceridemic men, the EPC counts and activity, as well as levels of NO, were significantly reduced. The values of VEGF and GM-CSF were without statistical change. Conclusions. The present study firstly demonstrated that there were sex differences in the number and activity of circulating EPCs in hyperglyceridemia patients. Hypertriglyceridemic premenopausal women displayed restored endothelial functions, with elevated NO production, probably mediated by estradiol. We provided a new insight to explore the clinical biomarkers and therapeutic strategies for hypertriglyceridemia-related vascular damage.
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