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The use of leafy vegetables in diet is a common practice among the people of the Northern ethnic groups of Ghana. In this study, a survey was conducted in the Bunkpurugu-Yunyoo district and Kanvilli of the Tamale Metropolis of the Northern Region of Ghana, to document the indigenous leafy vegetables routinely consumed as part of their alimentary culture. The phytochemical content, proximate composition and antioxidant properties of the plants cited were assessed. Nine leafy vegetables: Amaranthus cruentus, Hibiscus sabdariffa, Corchorus olitorius, Vernonia amygdalina, Phaseolus vulgaris, Ipomoea batatas, Adansonia digitata, Moringa oleifera and Annona reticulate were inventoried. These plants contained various groups of phytochemicals and were generally rich in carbohydrates, protein and fibre, but low in fat. They contain an appreciable amount of energy and also demonstrated good antioxidant activities. These characteristics of the vegetables suggested their usefulness in the maintenance of good health, which may also explains why these groups of Ghanaians in the Northern region are regarded as being very strong and healthy.