Poster Presentations P263and professional life; (2) Motivating factors for choosing surgery; (3) Patient knowledge; (4) Postoperative challenges; (5) Impact of OSA surgery.Conclusions: Patients' experiences going into the surgery can largely influence their perceived outcome and satisfaction. These experiences are individual and subjective, and the postoperative sleep studies do not capture the whole outcome of the patients' response to surgery. This suggests when patient reported outcomes are combined with postoperative sleep studies, otolaryngologists can gain a much better perspective about their patients.Objectives: Compare polysomnography (PSG) results before and after transoral robotic lingual tonsillectomy (TORLT) in patients with obstructive sleep apnea (OSA).Methods: Lingual tonsillar or base of tongue hypertrophy can be a cause of OSA but has proven difficult to address because of difficulty in accessing this area of the oropharynx through traditional surgical techniques. TORLT provides a simple, minimally invasive surgical technique for lingual tonsillectomy. Patients with OSA symptoms were assessed with preoperative PSG and sleep endoscopy for base of tongue obstruction. Selected candidates underwent TORLT followed by repeat PSG and nasal endoscopy after full recovery from the procedure. The pre-and postoperative PSG data were compared for each patient. Nonparametric comparisons were made using the signed rank test becasue of small sample size.Results: Ten patients underwent preoperative PSG and subsequent TORLT. Postoperative polysomnography data as available for 8 patients. Pre-and postoperative PSG comparisons (pre, post, P value) showed improvements in the median apnea-hypopnea index (49.8, 19.5, P = .84), sleep onset latency (11.8 minutes, 17.5 minutes, P = .84), sleep efficiency (80.5%, 92.3%, P = .2), and Epworth Sleepiness Scale (14.5, 10, P = .88), but none were statistically significant.Conclusions: Transoral robotic lingual tonsillectomy improved polysomnography measures but not to a level of significance. This study is limited by small sample size and associated limited statistical power. Further study with larger sample sizes should be undertaken to more definitively study outcomes for this surgical technique. Prevalence of High Risk for Obstructive Sleep Apnea using STOP-Bang Questionnaire in Thai PopulationNatamon Charakorn, MD (presenter); Prakobkiat Hirunwiwatkul; Apasee Suksamran, MD; Busarakum Teerapraipruk, MD; Naricha Chirakalwasan, MD Objectives: Determine the prevalence of high risk for obstructive sleep apnea (OSA) in general Thai population by using the STOP-Bang questionnaire. Methods: Anonymous survey was conducted in Thailand atHealth and Wellness exhibition. The exclusion criterion was age <18 years. The STOP-Bang questionnaire was used in the survey. This questionnaire consisted of 4 simple yes/no questions: snoring, tiredness, observed apneas, blood pressure, and 4 clinical characteristics which were dichotomized according to specified cutoffs; body mass index >35, age >...

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Objectives: Determine the human papillomavirus (HPV) infection and p53 protein expression in oral squamous cell carcinoma (OSCC) and their correlation with patient overall survival (OS) and disease-free survival (DFS).Methods: HPV general and type specific 16 and 18 were investigated by means of PCR. P53 protein overexpression was investigated by means of immunohistochemistry. Results of HPV association and p53 overexpression were evaluated in relation to different clinicopathological parameters and survival.Results: Out of 140 patient samples HPV was detected in 95 (68%) cases, out of which 85 (90%) were associated with HPV16, 2 (2%) were associated with HPV 18, 2 (2%) were co-infected (with HPV 16 and 18), and 6 (6%) were positive for HPV by the general primer and could not be type specified. HPV positive patients had comparatively prolonged OS when compared with HPV-negative patients, but this difference was not statistically significant (P = .97). Furthermore, overexpression of p53 protein was observed in 75 patients (54%) using a threshold of 10% stained tumor nuclei. Patients with p53 negative tumors had improved OS when compared with patients with p53 positive tumors. This difference was statistically significant (P = .036) in univariate Cox regression analysis; however, it lost its worth in the multivariate analysis.Conclusions: Our study found a high prevalence of HPV (type 16) in OSCC of Pakistani patients with male sex showing significant correlation with HPV. However, we did not find a statistically significant favorable association between p53 overexpression, HPV, survival, and histologic variables. Impact of Thyroid Molecular Testing with Surgeon Performed FnAC and Immediate On-Site Cytopathological InterpretationRay Sukumor, MD (presenter); Robert L. Witt, MD; Fady Gerges, MD Objectives: (1) Describe how thyroid molecular testing affects surgeon-performed ultrasound-guided fine-needle aspiration (FNA) with immediate on-site cytopathological interpretation.(2) Analyze percentage of inadequate FNA cytology (FNAC) and number of aspirations, comparing with and without surgeon-performed ultrasound guidance.Methods: Retrospective cohort comparison. A cytopathologist is present for on-site staining (Diff-Quik) adequacy evaluation and molecular testing triage. This is followed by pap stain, cell block, and liquid-based cytology. Cytological adequacy and number of aspirations for 200 consecutive patients undergoing surgeon-performed ultrasound-guided FNA are compared with a series from the same surgeon without ultrasound guidance. A questionnaire subjectively scoring anticipated and actual pain from 1 through 10 (10 severe) was recorded immediately before and after FNAC.Results: Patients with an inadequate FNAC, with and without ultrasound guidance, were 0% and 3% (P > .05). The mean number of aspirations with and without ultrasound guidance were 1.7 and 4.0 (P < .05). Using ultrasound guidance, benign, indeterminate, and malignant FNA results were 173 out of 200 (87%), 18 out of 200 (9%), and 9 out of 200 ...