A platform of highly efficient synthetic methodologies has been established to access a focused library of substituted 1,4‐naphthoquinones derivatives functionalized with a diversity of amino/hydroxy/alkyl groups. Furthermore, the structure–activity relationship deduced from antiproliferative activities and toxicities of this 1,4‐naphthoquinone library and intracellular reactive oxygen species (ROS) level detections might warrant future potential of plumbagin (2) and compound 13 as promising basic structures to develop novel anti‐cancer agents.

No abstract

No abstract

No abstract

Based on the panel data of Guangdong from 2005 to 2019, this paper makes an empirical study on the impact of industrial structure upgrading on Guangdong's export scale. The result shows that when the Theil index increases by 1 percentage point, the export will decrease by 3.15 percentage points. The closer the Theil index is to 0, the higher the rationalization of industrial structure is; The upgrading level of industrial structure has a negative impact on export. When the upgrading level of industrial structure increases by 1 percentage point, export will decreases by 1.08 percentage points. The reason is that enterprises are easy to fall into "export dilemma" in the process of industrial upgrading. Therefore, it is suggested that Guangdong should rationalize its industrial structure and attach importance to regional heterogeneity in order to expand its export scale.