No abstract

The title pyrimidine derivative, C18H21N3O6, was obtained by the reaction of methyl 2-[2-(benzyl­oxycarbon­yl)amino­propan-2-yl]-5-hy­droxy-6-oxo-1,6-dihydro­pyrimidine-4-carboxyl­ate with dimethyl sulfate in dimethyl sulfoxide. The mol­ecule has a V-shaped structure, the phenyl and the pyrimidine rings making a dihedral angle of 43.1 (1)°. The methyl group substituting the pyrimidine ring deviates slightly from the ring mean-plane [C—N—C—C torsion angle = 5.49 (15)°], and the methyl ester substituent has a conformation suitable for the formation of an intra­molecular O—H⋯O hydrogen bond with the hydroxyl functionality. In the crystal, molecules are linked into chains along the b axis by N—H⋯O hydrogen bonds.

In the title compound, C17H19N3O6, the dihedral angle between the two aromatic rings is 45.9 (1)°. The crystal structure is stabilized through inter­molecular N—H⋯O hydrogen bonds and intra­molecular O—H⋯O hydrogen bonds are also present.

No abstract