The sharp Zn dendrites tend to pierce through the separator and result in a short circuit of the battery, which disables electronic devices. [3] Generally, Zn dendrites are easily formed on the common planar conductive hosts with low surface area due to their excessive local current density and unrestricted 2D diffusion of Zn 2+ . [4] Various strategies have been adopted to inhibit Zn dendrites growth, such as electrolyte optimization, [5] surface modification, [6] and structural design. [7] For electrolyte optimization, concentration control, "water in salt", and additives for electrostatic shielding are used to improve the performance of the battery. For surface modifications, there are several effective methods like atomic layered deposition, solution soaking, and slurry casting. From the structural design strategy, construction of 3D high-surface-area zinc anode is considered as an effective way to restrain the dendrite formation. [8] For instance, 3D sponge Zn, electrodeposited Zn nanostructures on 3D current collectors, and dual-channel porous Zn are proven to effectively inhibit Zn dendrite growth. The increased surface area of 3D conductive host can reduce local current density and homogenize interfacial charge distribu-
Ultraflexible and ultralight rechargeable aqueous Zn-ion batteries (ZIBs) with the merits of environmental benignity and high security arise as promising candidates for flexible electronic systems. Nowadays, the energy density and cyclical stability of ZIBs on metal-based rigid substrates reach a satisfactory level, while the inflexible substrates severely prevent them from widespread commercial adoption in portable electronics. Although flexible substratesengineered devices burgeon, the development of flexible ZIBs with high specific energy still faces great challenges. Herein, a flexible ultrathin and ultralight Zn micromesh (thickness of 8 µm and areal density of 4.9 mg cm −2 ) with regularly aligned microholes is fabricated via combining photolithography with electrochemical machining. The unique microholes-engineered Zn micromesh presents excellent flexibility, enhanced mechanical strength, and better wettability. Moreover, numerical simulations in COMSOL and in situ microscopic observation system certify the induced spatial-selection deposition of Zn micromesh. Accordingly, aqueous ZIBs constructed with polyanilineintercalated vanadium oxide cathode and Zn micromesh anode demonstrate exceptional high-rate capability (67.6% retention with 100 times current density expansion) and cyclical stability (maintaining 87.6% after 1000 cycles at 10.0 A g −1 ). Furthermore, the assembled pouch cell displays superb flexibility and durability under different scenarios, indicating great prospects in high-energy ZIBs and flexible electronics.
Piezoelectric organic films as flexible and wearable pressure sensors are ideal materials for manufacturing of electronic skin. Poly‐l‐lactic acid (PLLA)/graphene composite nanofibers are fabricated by electrospinning. The relative crystallinity of the PLLA/graphene electrospun composite nanofibers increases from 9% to 30%. The d14 value of sample K0.1 (d14 = 9.02 pC N−1) increases by 2048% compared with sample K0 (d14 = 0.42 pC N−1). Piezoelectric bioelectronic skin is fabricated using the PLLA/graphene electrospun nanofiber mat, polyester fabric, and poly(dimethylsiloxane) (PDMS). The maximum open‐circuit voltage (Voc) and short‐circuit current (Isc) of the wearable sensors are 184.6 V and 10.8 μA. The response generated by touching the bioelectronic skin can be converted to a digital signal. The piezoelectric bioelectronic skin is used to monitor the pulse of the human body. Based on the results, a pulse of 76 beats min−1 is calculated, which coincides with the normal human heart rate interval (60–100 beats min−1). The addition of graphene influences the fiber diameters, thermal stability, relative crystallinity, and the piezoelectric properties along the fiber axial direction (d14) of PLLA. This small, flexible sensor, which can achieve high sensitivity, can be used for physiological and health care monitoring phonetic recognition.
Tumour invasion is closely related to the prognosis and recurrence of glioblastoma multiforme and partially attributes to epithelial‐mesenchymal transition. Long intergenic non‐coding RNA 00511 (LINC00511) plays a pivotal role in tumour; however, the role of LINC00511 in GBM, especially in the epigenetic molecular regulation mechanism of EMT, is still unclear. Here, we found that LINC00511 was up‐regulated in GBM tissues and relatively high LINC00511 expression predicted poorer prognosis. Moreover, ectopic LINC00511 enhanced GBM cells proliferation, EMT, migration and invasion, whereas LINC00511 knockdown had the opposite effects. Mechanistically, we confirmed that ZEB1 acted as a transcription factor for LINC00511 in GBM cells. Subsequently, we found that LINC00511 served as a competing endogenous RNA that sponged miR‐524‐5p to indirectly regulate YB1, whereas, up‐regulated YB1 promoted ZEB1 expression, which inversely facilitated LINC00511 expression. Finally, orthotopic xenograft models were performed to further demonstrate the LINC00511 on GBM tumorigenesis. This study demonstrates that a LINC00511/miR‐524‐5p/YB1/ZEB1 positive feedback loop provides potential therapeutic targets for GBM progression.
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