Post-operative recurrence and metastasis of malignant tumors are difficult to control, which probably results from multiple factors that affect the prognosis and the undefined mechanism. Anesthesia may be an influential factor. Researchers have performed many meaningful studies on the relationship between anesthetic drugs/methods and tumor growth/immune function, which provide important references for the anesthetic selection and peri-operative management of tumor patients. Anesthetics, analgesics, and sedatives should be used with caution because their effects in post-operative patients remain controversial. This review summarizes the emerging progress on the effect of anesthesia on post-operative tumor recurrence and metastasis, particularly focusing on the effects of anesthetic drugs, anesthetic methods, and post-operative analgesia on tumor growth and metastasis. Future studies should provide strict criteria for the proper use of anesthetics in patients with malignant tumors and provide experimental evidence for the improvement and development of novel anesthetics and anesthetic methods that have the important clinical significance.

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Countrywide and worldwide business, like gaming and social networks, drives the popularity of inter-data-center transactions. To support inter-data-center transaction processing and data center fault tolerance simultaneously, existing protocols suffer from significant performance degradation due to high-latency and unstable networks. In this paper, we propose RedT, a novel distributed transaction processing protocol that works in heterogeneous networks. In detail, nodes within a data center are inter-connected via the RDMA-capable network and nodes across data centers are inter-connected via TCP/IP networks. RedT extends two-phase commit (2PC) by decomposing transactions into sub-transactions in terms of the data center granularity, and proposing a pre-write-log mechanism that is able to reduce the number of inter-data-center round-trips from a maximal of 6 to 2. Extensive evaluation against state-of-the-art protocols shows that RedT can achieve up to 1.57× higher throughputs and 0.56× lower latency.

ResumenEn Dahecun, un