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Objective We evaluated efficacy of mHealth technology for reducing cardiovascular risk among metabolic syndrome individuals in India. Methods We screened 1012 adults in 10 villages (clusters) in north-west India for presence of metabolic syndrome. Participants with inclusion criteria were randomized. Ownership of cell-phone was essential. We developed user-friendly interactive voice response system in Hindi based on transtheoretical model of behavior change. Two messages for promotion of healthy lifestyle and medical treatments were broadcast daily over 12-months in intervention clusters and queries answered. Lifestyle and biochemical factors were assessed at baseline and at 12-months. Results 1012 rural individuals aged 20–60y in 10 villages were screened, majority were women (53%) and less literate (76%). Metabolic syndrome was in 286 (28.3%). These were divided into 5 control (n=136) and 5 intervention (n=147) clusters. Baseline characteristics in participants in control and intervention clusters were similar. At 12 months, significantly greater participants in intervention clusters had better lifestyle features and lower waist circumference, body mass index, systolic BP, fasting glucose, cholesterol and triglycerides (Table). Conclusion An interactive voice response system based technology significantly reduced multiple cardiovascular risk factors in metabolic syndrome individuals in rural India. Funding Acknowledgement Type of funding source: None

BACKGROUND Visual rehabilitation of aphakic patients include spectacle correction, contact lenses, and primary or secondary intra ocular lens (IOL) implantation. Spectacles are rarely used nowadays because of limited visual field, aniseikonia and peripheral refractive errors. Contact lenses are other options for correcting aphakia but can cause a lot of corneal complications. Options for correction of aphakic patients with lack of adequate capsular support include anterior chamber IOL (ACIOL), scleral fixated IOL (SFIOL), and iris fixated IOL. Implantation of a retropupillary IC-IOL provides the benefits of a PCIOL, and the duration of the surgery is also less. The retropupillary IC-IOL because of its position lowers the risk of endothelial decompensation is a better option. We wanted to evaluate the functional outcomes of retropupillary iris claw lens implantation. METHODS Secondary implantation of IC-IOL was done in 50 surgical aphakic eyes as a result of intraoperative posterior capsular rent with zonular dialysis (N = 43, 86 %) & large (> 7 clock hours) zonular dehiscence (N = 7, 14 %). Follow up was done on 1 st day, 7th day, 1 month, 3 months and 6 months. RESULTS 22 males and 28 females in the age group 40 - 78 years were operated. 78 % eyes (N = 39) had vision better than 6 / 12 while only 10 % eyes (N = 5) had < 6 / 60 vision and the remainder 12 % (N = 6) had vision between 6 / 18 & 6 / 36. Complications like acute postoperative iritis (N = 18, 36 %) pupillary distortion (N = 15, 30 %), pigment clumping (N = 10, 24 %), iris chaffing (N = 9, 21 %), secondary glaucoma (N = 5, 12 %) and IOL decentration (N = 3, 7 %) were seen. The mean difference in central endothelial counts before surgery and 6 months after surgery was 109 cell / mm2 (5.92 %). CONCLUSIONS Iris claw lens gives the dual benefit of good visual acuity and less complication rate in aphakic patients with lack of adequate capsular support. KEYWORDS Retropupillary Iris Claw Lens, Surgical Aphakia, Secondary implantation, Zonular Dialysis, Aneisokonia