Background: Chronic obstructive pulmonary disease (COPD) is a common, preventable and treatable disease. Tobacco, smoking, occupational exposure to organic and inorganic dusts, chemical agents and fumes and biomass cooking are the risk factors for COPD. Chronic dyspnoea, cough, sputum production, wheezing and chest tightness are the common symptoms of COPD. Aim: The present study was undertaken to evaluate the clinical profile of COPD patients in central India. Methods: This was a prospective study of 250 patients of COPD who presented to out- patient department. Spirometry was performed to confirm the diagnosis.  Detailed history of risk factors, age, socio-economic status and clinical examination was done for every patient. Results: Out of the 250 patients, majority was between 40-60 years of age, with male predominance (75.6%). Prevalence of COPD was more in rural and low socio-economic status patients. History of smoking was present in 65.2% patients. Commonest symptom was dyspnoea (in 96.4% patients) followed by cough (76.8%), sputum production (59.9%), wheezing (42.8%), chest tightness and fever (26.8%) and weight loss (19.2%). Hypertension was present in 18.8% patients. Conclusions: Prevalence of COPD was seen predominantly in male patients. Tobacco smoking was the commonest etiological factor.

Background: Malaria is the commonest parasitic infection in India. A shift in the clinical profile in patients with complicated malaria has been observed with multiple organ dysfunctions becoming a common feature. Aim: This study is aimed to evaluate the clinical profile of malaria in a tertiary care hospital, central India. Material and Methods: A prospective study was carried out at a tertiary care hospital of a medical college in M.P. India. Patients of 18 years age or above who were smear positive or antigen positive were included in the study. Results:  A total of 230 malaria cases were present, of which 54.8% were males. The mean age of the participants was 34.7 years. Prevalence was common in rural (64.8%) and lower socio-economic class (46.1%) population. Fever weakness/nausea and headache were the most common presenting complaints (94.3% and 85.7% and 71.3% respectively) and pallor, jaundice and hepato splenomegaly were the foremost sign. Plasmodium Vivax (53%) was the most common infection. Conclusion: Malaria has a male preponderance. Fever, headache, weakness, pallor and splenomegaly were the common clinical presentation.