:Postoperative nausea and vomiting (PONV) is common after anaesthesia and surgery. In patients undergoing laparoscopic cholecystectomy (LC) without antiemetic prophylaxis, the incidence can be as high as 76% which would cause unexpected delay in hospital discharge. This study was designed to compare the efficacy of the ondansetron alone with combination of ondansetron and dexamethasone the given as prophylaxis for PONV in patients undergoing laparoscopic cholecystectomy. One hundred patients undergoing elective laparoscopic cholecystectomy were selected and randomly divided into 2 groups of 50 each. Group I received 4mg of ondansetron intravenously (iv), whereas Group II received ondansetron 4mg and dexamethasone 4mg just before induction of anaesthesia. Postoperatively, the patients were assessed for episodes of nausea, vomiting and need for rescue antiemetic. Complete response defined as no nausea and vomiting during first 24 hours, was noted in 76% of patients in Group I and in 92% of patients in Group II. Rescue anti emetic requirement was less in Group II (4%) than Group I (20%). So it can be concluded that the combination of ondansetron and dexamethasone is more effective in preventing PONV in patients undergoing laparoscopic cholecystectomy than ondansetron alone.
Different pattern of trend in WPI and CPI numbers over years is found to be depicted periodically for Indian economy. This has implication for casting impact on supply price determination while purchasing power of consumers can be chalked about from trend in their per capita income which also demonstrates variation over years.Movement of these indices may focus on ongoing changes taking place in exchange activities as well as may point towards price determination mechanism operating in economic system. An effort has been made in preparing framework of this paper to analyse and explore various contemporary socio-economic changes ushered in by movement of WPI and CPI indices over years and its impact fell on nature of transaction, places of transaction and network of transaction.
Educational achievement and age correlatives may have significant bearings on generation, maintenance, and sustenance of environment to disseminate education for comprehensive development of learners as permeation of learning and its diffusion rate may vary depending upon different achievements on literacy scale for different age groups. More so, for disable learners as such learners need additional initiatives and assisting environment of even more literate fellow beings constituting surroundings. From this perspective, this paper makes a descriptive analytical effort to present census (2011) results in evaluating overall literacy position and that for disable ones alongwith environment availability through simple statistical tools.
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