Infertility associated with Poly Cystic Ovarian Syndrome (PCOS) is a major cause of concern in the present generation among the reproductive age groups due to undesirable lifestyle changes. This is a case report of an infertile couple who had not been able to conceive since 11 yrs. The wife was diagnosed with PCOS. They underwent conventional treatments of primary infertility including IUI (Intra Uterine Insemination) and hormonal therapy both the treatments were unsuccessful. The objective of the present treatment included Ayurvedic management of PCOS, ensuring regular ovulation and thereby helping to develop healthy pregnancy and successful childbirth. Based on the parameters of Ayurvedic science this case was diagnosed as Vandhyatva (Infertility) due to Nashtartava (Amenorrhea). Treatment plan included both Shodhana (Purification) and Shamana (mitigation) therapies. During the treatment period she lost 20 kg of weight and regained regular menstruation thereafter. The outcome of the Ayurvedic intervention was the conception of the patient within 8 months of treatment and delivery of a healthy baby girl.

Ayurveda has described many a psychiatric disorders in different contexts. Unmada is an entity where there is derangement of mind, cognition, orientation, memory, desire, habits, actions and rituals, either individually or as a whole. All of the above faculties are not impaired in a single clinical entity. Obsessive compulsive disorder (OCD) can be considered due to deviation of the mental attributes like cognition, will power, memory etc. which affects the day to day life of an individual. Management of psychiatric disorders in Ayurveda includes spiritual therapy, psychotherapy and pharmacotherapy focusing on the balancing of bodily and mental humors. Here in the case of OCD, vaata is the main humor vitiated among the three basic humors and the management should be directed to pacify all the three humors, with special consideration to vaata. Snehapaana is the important one among them. In the case of thought abnormalities, mental functions will be fogged up. To cleanse the channels, the drug of choice should be pungent and having the property of srotosodhana i.e. clearing the channels. The selected drug in this study, Pancagavya ghrita is an ideal drug in that sense. The aim of this study was to assess the efficacy of Pancagavya ghrita in OCD when compared with the supportive psychotherapy. The method of this study is randomized controlled trial with sample size 20; assessments were done according to Yale Brown Obsessive Compulsive Scale. There were significant changes in the trial group and the control group. But there was no statistical significance on comparison between the two groups.

Mental Retardation is a state of developmental deficit, beginning in childhood, resulting insignificant limitation of intellect or cognition and poor adaptation to the demands of everyday life. It is not always a disease but the consequence of some pathogenic process, resulting in a lifelong disability. Abundant research works are going on around the globe and a multidisciplinary approach incorporating different level of management strategies including the parent and the society is the primary option nowadays. Ayurvedic parlance is really a treasure of several therapeutic combinations advisable in conditions like Mental Retardation. Many drugs are being handled in clinical practise with positive claims. Behaviour modification therapy is a proven method capable of improving the overall performance of children with mental sub normalities, if performed with professional excellence. Ashtamangala gritha mentioned in baalaroga chikitsa in Bhaishajya ratnavali had been selected as study drug for this Randomised Controlled Trial (RCT). Behaviour modification therapy had been tried against its efficacy with the selected gritha as it is a proven therapy. The study was conducted with 40 subjects. The study group with Ashtamangala gritha along with Behaviour modification therapy was tried against the control with only Behaviour modification therapy. Assessment was done before treatment, after 30 days of treatment and after 30 days of follow up. The assessment was done using the Malin's IQ Scale and Madras Development Programming System (MDPS) scoring. It was observed that Ashtamangala gritha has significant effect in the improving the IQ of children with Mental Retardation.

Dementia is a syndrome due to degeneration of the cerebral cortex, usually of a chronic or progressive nature, in which there is disturbance of multiple higher cortical functions, including memory, thinking, orientation, calculation, comprehension, capacity to learn, language skills and judgment. Alzheimer’s dementia, Frontotemporal dementia, dementia with lewy bodies, vascular dementia, Huntington’s dementia and Parkinson dementia are the types of dementia. Alzheimer’s dementia is the most common one among the category. The prevalence of depressive symptoms in dementia is 30% and is presented with symptoms such as poor appetite, sleep perversions and social withdrawal. Features of Smrti vibhrama and characteristics of Pranavrta vyana are being observed Alzheimer’s dementia. There is still no effective cure for dementia in contemporary medicine. So, developing an Ayurvedic protocol to treat dementia is a necessity. This is the case of a 72-year-old male presented with loss of interest in daily activities, fatigue, reduced appetite and increased sleep for duration of 7 months and underwent treatment for 1 month. Diagnosis was done based on the criteria in DSM 5 and the severity was assessed by Mini- mental status Examination and Hamilton’s Depression Scale. The management was a combination of modalities including Deepana, Pacana, Virecana, Nasya and follow-up of 1 month. The treatment modalities were found to be effective in the cognitive and depressive symptoms as well as improving the social behaviour in dementia patient.

Ulcerative Keratitis is a sight-threatening corneal infection. It is one of the most common global causes of irreversible blindness due to corneal diseases. This case report highlights the potential of Ayurvedic management in nonresponding ulcerative keratitis. A 20 year old boy came to the outpatient department with redness, discharge, photophobia and defective vision in the right eye since 4 months following a foreign body injury. He was treated at leading ophthalmic hospital for keratitis but due to poor response was suggested keratoplasty and the patient had opted for Ayurvedic treatment. He was initially treated in the OPD and since he started responding well to treatment, he was admitted in the hospital. He underwent Jaloukavacharana, Snehapana, Virechana, Nasya, Anjana, Tarpana and Putapaka. He was completely relieved of pain, redness, discharge, photophobia. His BCVA was hand movements at the time of the first visit and it improved to 6/24 at the time of discharge. Ayurveda has an important role to play in infective eye diseases which needs to be explored scientifically.