During the high-Mach-number, high-altitude portion of the first entry of the Shuttle Orbiter, the vehicle exhibited a nose-up pitching moment relative to preflight prediction of approximately ACre = 0.03. This trim anomaly has been postulated to be due to compressibility, viscous, and/or real-gas (lowered specific heat ratio "7) effects on basic body pitching moment, body-flap effectiveness, or both. In order to assess the relative contribution of each of these effects, an experimental study was undertaken to examine the effects of Mach number, Reynolds number, and ratio of specific heats. Complementary computational solutions were obtained for wind-tunnel and flight conditions. The primary cause of the anomaly was determined to be lower pressures on the aft windward surface of the Orbiter than deduced from hypersonic wind-tunnel tests with ideal-or near-ideal-gas test flow. The lower pressure levels are a result of the lowering of the flowfield "7due to high-temperature effects. This phenomenon was accurately simulated in a hypersonic wind tunnel using a heavy gas, which provided a lower "7,and was correctly predicted by Navier-Stokes computations using nonequilibrium chemistry.