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Study design: Cross-sectional validation study. Objectives: To adapt the Spinal Cord Lesion-related Coping Strategies Questionnaire into the Spanish language (SCL CSQ-S) and to examine the relationship between coping strategies, global quality of life and psychological adaptation. Setting: Data were collected through individuals with spinal cord injury (SCI) now living in the community who completed their routine follow-up assessment at the Institute Guttmann in Barcelona, Spain. INTRODUCTIONSpinal cord injury (SCI) is one of the primary causes of neurological disability in Spain. In fact, it is estimated that there are 12-20 new cases of SCI per million inhabitants per year. Thus the overall prevalence of SCI in Spain is approximately 350 individuals per million inhabitants. 1 SCI represents a long-term medical condition that produces irreversible physical, psychological and social consequences. Therefore, SCI individuals are forced to continuously adapt to their condition by making adjustments within several specific domains, including mobility, self-care, lifestyle and social relations. 2,3 Indeed, the psychological impact of SCI is evidenced by the fact that there is a higher incidence of anxiety and depression in affected individuals when compared with the general population. 4 The use of coping strategies has been identified as an important mechanism by which SCI individuals adjust to their state of chronic disability. 5,6 Notably, SCI-related coping strategies were found to impact psychological variability more than socio-demographic or lesion-related factors. 6 Nevertheless, methodological limitations, such