Using human-centered design (HCD), key learnings identified opportunities for intervention to promote viral suppression and improve ART adherence and retention in care among adolescents and young people living with HIV (AYAHIV). Opportunities included fostering a sense of belonging and peer connectedness with other AYAHIV, providing contextually resonant medical knowledge that fits the unique context of adolescence and young adulthood, reducing misconceptions and stigma surrounding HIV, and cultivating a sense of hope for AYAHIV.n Intervention components include a media campaign to reduce HIV stigma and increase medical literacy; a toolkit to help providers communicate and address the unique needs of AYAHIV clients; peer-support groups to improve medical literacy, empower youth, and provide positive role models for people living with HIV; support groups for parents/caregivers; and discreet pill containers to promote adherence outside the home.