Introduction: The next case report corresponds to a female patient of 30 years and 12 days old from the canton of La Troncal and mixed ethnicity on admission to the right lumbar fossa with the presence of a 5 cm orifice with a large amount of fetid purulent content that evolves to a diagnosis of septic shock of urinary vs. abdominal origin, acute perforated abdomen and retroperitoneal collection, for which on November 30, 2022 an exploratory laparotomy, ileostomy, right hemicolectomy, right nephrectomy, retroperitoneal collection drainage and drain placement were performed. Jackson Pratt's patient remains under sedoanalgesia with midazolam and fentanyl RASS -4. She is coupled to mechanical ventilation, afebrile with antibiotic therapy with meropenem and vancomycin, who presents elevated acute phase reactants with rising leukocytosis and neutrophilia. In addition, the culture revealed the presence of Gram-negative bacilli in the surgical wound. Case report: to present a complex clinical case where the post-surgical patient's condition was complicated, causing septic shock Conclusion: post-surgical complications are rare; however, they can be deadly and very complicated to treat, which urges health professionals to take the necessary measures to minimize this postoperative risk.