HighlightsBowel ischemia and necrosis is an uncommon complication of anorexia nervosa.We present a case of a 30 year old woman with long-standing AN complicated by ischemia and necrosis of the entire small bowel and the right hemicolon.A high index of suspicion of bowel ischemia is necessary when patients with AN present with abdominal symptoms.Timely diagnosis and treatment may prevent bowel necrosis and death.

Beta-adrenoceptor blockade increases serum K, which may be related to renin inhibition, hypoaldosteronism, and exercise-induced skeletal muscle release of serum K. We report on the dynamic and biochemical response to clonidine (C) after single (S) 0.2-mg and repeated (R) 0.1-mg bid doses of C to six normal subjects at rest, 2 hr after dosing and immediately before dynamic physical activity (DPA) on a treadmill, and at peak activity and 2 hr after DPA. Blood pressure (BP), heart rate (HR), plasma renin concentration (PRC), aldosterone (ALD), serum K, epinephrine (E), and norepinephrine (NE) were measured in standing subjects before and 2 hr after placebo or C (S or R), at peak DPA, and 2 hr after exercise. K, BP, and HR were also determined during all stages of DPA. Results show a parallel rise in K at peak over rest after C (S or R) and after placebo. NE, E, and PRC decreased after 1 wk of C (P less than 0.01), but the fall of ALD was only slight. The fall in NE at rest suggested a relationship to the decrease in systolic BP and rate pressure product after 1 wk on C. With DPA there is a normal yet smaller increase in systolic BP and also a smaller rise in HR with S- and R-dose C. There is no adverse rise in K in C-treated subjects during DPA.

Glomus tumor is a benign mesenchymal neoplasm comprising less than 2% of soft tissue tumors. The usual locations for glomus tumors are the digits, where the glomus bodies are normally present. They have been reported in extradigital sites, including bone, lung, intestinal tract, and breast. In the inguinal region, it is rarely reported and one patient with multiple (four) glomus tumors of inguinal region has been described by Antonio et al in 2002. We report a case of a 53-year-old man who presented with left lower limb pain and was found to have an enlarged left inguinal soft tissue mass mimicking a lymph node on venous duplex scan. He underwent an excisional biopsy and revealed a 1.2-cm soft tissue mass in the left inguinal region that was sent for histological diagnosis. Microscopic examination showed benign proliferation of small capillaries and blood vessels with nests of round uniform cellspericytes-glomocytes without evidence of malignancy or atypia. Immunohistochemical studies showed tumor cells positive for alpha smooth muscle actin and negative for CD 34 confirming the diagnosis of a glomus tumor. Schiefer et al described a 20-year experience of fifty six (56) extra digital glomus tumors in a single institution, and none was described in the inguinal region. This report widens the spectrum of the differential diagnoses for masses in inguinal region. Because of their rarity, there are no clear guidelines for follow-up of glomus tumors, but accurate diagnosis and understanding of usually benign behavior, are crucial for the management.