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The Banff Working Group on Liver Allograft Pathology reviewed and discussed literature evidence regarding antibody-mediated liver allograft rejection at the 11th (Paris, France, June 5-10, 2011), 12th (Comandatuba, Brazil, August 19-23, 2013), and 13th (Vancouver, British Columbia, Canada, October 5-10, 2015) meetings of the Banff Conference on Allograft Pathology. Discussion continued online. The primary goal was to introduce guidelines and consensus criteria for the diagnosis of liver allograft antibody-mediated rejection and provide a comprehensive update of all Banff Schema recommendations. Included are new recommendations for complement component 4d tissue staining and interpretation, staging liver allograft fibrosis, and findings related to immunosuppression minimization. In an effort to create a single reference document, previous unchanged criteria are also included.

A sample of 413 soundings in close proximity to tornadic and nontornadic supercells is examined. The soundings were obtained from hourly analyses generated by the 40-km Rapid Update Cycle-2 (RUC-2) analysis and forecast system. A comparison of 149 observed soundings and collocated RUC-2 soundings in regional supercell environments reveals that the RUC-2 model analyses were reasonably accurate through much of the troposphere. The largest error tendencies were in temperatures and mixing ratios near the surface, primarily in 1-h forecast soundings immediately prior to the standard rawinsonde launches around 1200 and 0000 UTC. Overall, the RUC-2 analysis soundings appear to be a reasonable proxy for observed soundings in supercell environments. Thermodynamic and vertical wind shear parameters derived from RUC-2 proximity soundings are evaluated for the following supercell and storm subsets: significantly tornadic supercells (54 soundings), weakly tornadic supercells (144 soundings), nontornadic supercells (215 soundings), and discrete nonsupercell storms (75 soundings). Findings presented herein are then compared to results from previous and ongoing proximity soundings studies. Most significantly, proximity soundings presented here reinforce the findings of previous studies in that vertical shear and moisture within 1 km of the ground can discriminate between nontornadic supercells and supercells producing tornadoes with F2 or greater damage. Parameters that combine measures of buoyancy, vertical shear, and low-level moisture show the strongest ability to discriminate between supercell classes.

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