This study examines how the concept of gender mainstreaming could influence the adoption of e-government services in Kenya, which like many other developing countries, the Kenyan e-government initiatives has faced a number of challenges since its inception. The study utilizes and expands on Technology Acceptance Model to explore the adoption of e-government services in the Siaya County of Kenya. A simple random sampling technique was used to select a sample size from the population and a questionnaire was used to collect data from the participants. Analysis of the demographic data was done to test the research hypothesis using descriptive statistics of frequency counts and percentage. The major findings of the study revealed that men are potential adopters of e-government services. This is exhibited by a positive correlation that was found after a regression done on gender in relation to E-government adoption. The findings of this study are meant to provide a better understanding of mainstreaming gender in order to engender the adoption of e-government services.