BACKGROUNDCalcium channel blockers are frequently used in management of essential hypertension, of which amlodipine is a common agent. Overdose of amlodipine results in refractory hypotension and non-cardiogenic pulmonary oedema. The mainstay of treatment involves glucose insulin drip, calcium supplementation and glucagon. Here, we report a case of a 25-year-old female with history of intake of 100 mg of amlodipine treated successfully with glucose insulin drips and calcium infusion. BACKGROUND Calcium Channel Blockers (CCBs) are considered to be the mainstay in management of hypertension. Amlodipine is a common dihydropyridine calcium channel blocker used in India in varying dose up to a maximum of 20 mg daily. Unlike other calcium channel blockers, amlodipine has a very low metabolic clearance with the advantage of using a once-daily dosage to maintain a near-constant plasma concentration. Owing to the easy availability, it is becoming a nemesis as it is being used for suicidal purposes by means of overdose. Proper management guidelines have not been formulated yet for this condition and different drugs including glucagon, insulin and calcium gluconate in titrated doses are being used with reasonable success rate. Here, we report a case of a 25-year-old female who presented with history of intake of 100 mg of amlodipine, was in hypotension and how she was managed successfully.