Gastroezofaginis refliuksas (GER) yra normalus fiziologinis reiškinys, pasireiškiantis daugiau nei pusei sveikų kūdikių. Tai dar dažnai vadinama „regurgitacija“ arba atpylimu, kuomet po maitinimo vyksta nedidelis arba gausesnis motinos pieno ar adaptuoto kūdikių mišinio ištekėjimas per lūpų kampą. Medicinoje šis fiziologinis reiškinys vadinamas GER arba refliuksu [5]. Papildomas tyrimas ir gydymas nereikalingas, nes šis reiškinys dažniausiai išnyksta savaime, kūdikiui augant. Tam tikrais sudėtingesniais atvejais gydymui rekomenduojamos nemedikamentinės priemonės.

Crohn's and Hirschsprung's diseases are two different conditions of intestinal tract though both of them are genetically predisposed. Each disease have genetic mutations in some genes, however there are no evidence that there are mutations common to both conditions. We present 3 clinical cases of patients who underwent surgery in infancy for Hirschsprung's disease. Later in early childhood all the patients developed clinical symptoms of inflammatory bowel disease and Crohn's disease was diagnosed. Both conditions were confirmed histologically. After introducing the treatment for Crohn's disease positive effect was shown. These cases raise the hypothesis that the two conditions may have similarities in etiology and pathogenesis and may represent a spectrum of intestinal inflammatory diseases in children.