Org 25969 effectively reversed a deep and prolonged neuromuscular block induced by rocuronium. The effective reversal dose appears to be 2-4 mg kg(-1).

We present a quasi‐liquid mediated continuum model for ice growth consisting of partial differential equations informed by molecular dynamics simulations. The main insight from molecular dynamics is the appearance of periodic variations in the equilibrium vapor pressure and quasi‐liquid thickness of the ice/vapor interface. These variations are incorporated in the continuum model as subgrid scale microsurfaces. We show that persistent faceted ice growth in the presence of inhomogeneities in the ambient vapor field is due to a spontaneous narrowing of terraces at facet corners, which compensates for higher ambient water vapor density via feedback between surface supersaturation and quasi‐liquid thickness. We argue that this emergent behavior has the mathematical structure of a stable limit cycle and characterize its robustness in terms of ranges of parameters that support it. Because the model is relevant in the high‐surface‐coverage regime, it serves as a useful complement to the Burton‐Cabrera‐Frank framework. Quantitative aspects and limitations of the model are also discussed.

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Motion control parameters of rotational molding can affect process efficiency and product quality. Different motion control schemes will lead to varied powder flow regimes exhibiting different levels of mixing and temperature uniformity. The change in nature of powder flow during a molding cycle suggests that varying the rotational speed could improve the powder mixing and temperature uniformity, therefore potentially reducing processing time and energy consumption. Experiments completed investigating powder flow under uniaxial rotation show that savings of up to 2.5% of the heating cycle time can be achieved. This validates the hypothesis that altering the rotational speed to maintain the ideal powder flow throughout the heating cycle can be utilized to reduce the time taken for all the polymer powder to adhere to the mold wall. The effect of rotational speed on wall thickness uniformity and impact strength were investigated and discussed. Results show a strong influence of rotational speed (and powder flow) on the wall thickness uniformity of the moldings with wall thickness uniformity deviations of up to 50% found (within the 2-35 RPM speed range tested).