This paper describes the application of an accessible, benchtop mass spectrometer using an Atmospheric Solids Analysis Probe (ASAP) for easy sample introduction, coupled with Atmospheric Pressure Chemical Ionization (APCI) as a soft ionization technique, to the inquiry-based identification of the metal composition of alloys, including coins. Students experience the preparation of metal acetylacetonates via traditional salt metathesis and electrochemical methods. They are then encouraged to immediately apply these newly acquired skills to a novel research problem. The discovery aspect of the practical demonstrates opportunities to develop experimental design early in the undergraduate curriculum.

A detailed investigation of the reactions of diaryldiazo compounds for the surface modification of several polymers has been conducted. This has revealed that the rate of reaction of diaryldiazo compounds is influenced by their substituents, that the reaction is exothermic, and that the polymer itself exerts an influence on the surface modification. The results are consistent with the formation and insertion of a carbene intermediate at the polymer surface. It was further shown that such surface modified polymers, characterized using surface sensitive techniques, display macroscopic behavior consistent with the presence of the newly introduced surface chemical functionality, characterized using a combination of surface sensitive and bulk analytical techniques. This approach is complementary to directed energy deposition approaches, offers an alternative route to functional polymers, and provide a direct link between surface chemistry and observable macroscopic properties.

Fused polyheterocyclic derivatives are available by annulation of a tetramate scaffold, and been shown to have antibacterial activity against a Gram-negative, but not a Gram-positive, bacterial strain. While the activity is not potent, these systems are structurally novel showing, in particular, a high level of polarity, and offer potential for the optimization of antibacterial activity.

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