This study examines the effect of an Integrated Student Support (ISS) intervention on postsecondary enrollment and completion for predominantly low-income and minority students. We use propensity score weighting to estimate the effect of receiving ISS during elementary school on postsecondary outcomes for 2009-2017 high school graduates from a large, urban district. Students who received ISS have higher probabilities of enrolling in and completing postsecondary education, and higher probabilities of enrolling in and graduating from four-year (versus two-year) institutions, than the comparison group. However, institution type differences may be sensitive to omitted variable bias. Together, results suggest ISS as an effective intervention to reduce barriers to postsecondary education and, thereby, to potentially reduce income- and race-based disparities in postsecondary outcomes.