We performed studies in 8-, 16-, 24-, 30 and 35-day-old Wistar rats at 8.00 h (AM) and 20.00 h (PM) to investigate the relationship between the diurnal variations of basal plasma corticosterone (compound B, CB) and its responses to ACTH and ether stress during the postnatal period. Basal plasma CB levels increased at PM from 8 to 35 days of age and an AM-PM difference was observed at 16 days. Although an AM-PM difference in CB responsiveness to ACTH was detected only at 24 and 35 days, ACTH induced an increasingly higher CB response at PM than at AM from 8 to 35 days. A stress-induced CB response was observed starting at 8 days of age and presented an age-dependent increase; however, no AM-PM difference was observed at any age. The stress-induced CB levels were higher than ACTH-induced CB values at all ages tested except at PM in 8-day old rats. These data demonstrate that the basal CB levels and adrenal sensitivity to ACTH rise during the evening as a function of neonatal development.

Resumo Resumen R E S E A R C H P A P E R ( O R I G I N A L )International academic mobility: an education opportunity for future nursesIntercâmbio académico internacional: uma oportunidade para a formação do futuro enfermeiro Intercambio académico internacional: una oportunidad de formación para los futuros enfermeiros Jordana Lopes Carvalho*; Dirce Stein Backes**; Maria de Lurdes Lopes de Freitas Lomba***; Juliana Silveira Colomé**** Background: International academic mobility allows for the exchange of scientific and cultural knowledge, namely on health technologies, the sharing of information and experiences, and the increase of professional opportunities. Objectives: To identify the benefits of international academic mobility for nursing education from the students' perspective. Methodology: We conducted an exploratory-descriptive study, with a qualitative approach, with a sample of 17 students who had participated in international mobility programs in the Franciscan University Center -Santa Maria/RS/Brazil and in the Nursing School of Coimbra/Portugal. Data were collected through semi-structured interviews and then submitted to content analysis.Results: Data analysis resulted in 3 categories: Health in the home country vs. health in the host country -contextualizing professional knowledge and experiences; Academic mobility -possibility for the development of students' autonomy; and Opening horizons -cultural contributions in the process of academic mobility. Conclusion: Academic mobility processes enable the contact with new clinical and research practices, which improves students' education and professional performance as future nurses.

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